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Product Details
PA5-100330
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SETBP1(Accession Q9Y6X0), corresponding to amino acid residues K586-V636.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2849844
Product Specific Information
Antibody detects endogenous levels of total SETBP1.
Target Information
This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SEB; SET binding protein 1; SET-binding protein
Gene Aliases: C130092E12; KIAA0437; mKIAA0437; MRD29; SEB; SETBP1
UniProt ID: (Human) Q9Y6X0, (Mouse) Q9Z180
Entrez Gene ID: (Human) 26040, (Rat) 291423, (Mouse) 240427
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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