Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Proteintech
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Immunogen sequence: KVTKQRDSE MGQQSLLFQI DYPEIAEGIM PRHRFMSAYE QRIEPPDRRW QYLLMAAEPY ETIAFKVPSR EIDKAEGKFW THWNRETKQF FLQFHFKMEK PPAPPSLPAG PPGVKRPPPP LMNGLPPRPP LPESLPPPPP GGLPLPPMPP TGPAPSGPPG PPQLPPPAPG VHPPAPVVHP PASGVHPPAP GVHPPAPGVH PPAPGVHPPT SGVHPPAPGV HPPAPGVHPP APGVHPPAPG VHPPAPGVHP PPSAGVHPQA PGVHPAAPAV HPQAPGVHPP APGMHPQAPG VHPQPPGVHP SAPGVHPQPP GVHPSNPGVH PPTPMPPMLR PPLPSEGPGN IPPPPPTN (118-464 aa encoded by BC004434)
This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: pre-mRNA splicing factor SF3A, subunit 2; SAP 62; SF3a66; spliceosomal protein gene 62; spliceosome associated protein 62; Spliceosome-associated protein 62; Splicing factor 3A subunit 2; splicing factor 3a, subunit 2, 66kD; splicing factor 3a, subunit 2, 66kDa
Gene Aliases: 66kDa; AW047242; PRP11; PRPF11; SAP62; SF3A2; SF3a66; SFA66
UniProt ID: (Human) Q15428, (Rat) Q6AXT8
Entrez Gene ID: (Human) 8175, (Mouse) 20222, (Rat) 299620
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