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Invitrogen
SF3B1 Recombinant Rabbit Monoclonal Antibody (JB40-32)
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Product Details
MA5-34649
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JB40-32
Immunogen
Recombinant protein within Human SF3B1 aa 1-105
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2848557
Product Specific Information
Positive Control: Mouse thymus tissue lysate, Hela, human colon cancer tissue, human skin tissue, human kidney tissue, mouse small intestine tissue.
Target Information
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex. The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: pre-mRNA processing 10; pre-mRNA splicing factor SF3b, 155 kDa subunit; Pre-mRNA-splicing factor SF3b 155 kDa subunit; SAP 155; SF3b155; Spliceosome-associated protein 155; Splicing factor 3B subunit 1; splicing factor 3b, subunit 1, 155kDa
Gene Aliases: Hsh155; MDS; PRP10; PRPF10; SAP155; SF3B1; SF3b155
UniProt ID: (Human) O75533
Entrez Gene ID: (Human) 23451
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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