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Invitrogen
SF3B14 Polyclonal Antibody
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SF3B14 Antibody (PA5-57078) in IHC
Immunohistochemical staining of SF3B14 in human breast, kidney, lymph node and skeletal muscle using SF3B14 Polyclonal Antibody (Product # PA5-57078) (A) shows similar protein distribution across tissues to an independent SF3B14 Polyclonal Antibody (B).
Product Details
PA5-57078
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SF3B6. Recombinant protein control fragment (Product #RP-96002).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2647183
Product Specific Information
Immunogen sequence: MAMQAAKRAN IRLPPEVNRI LYIRNLPYKI TAEEMYDIFG KYGPIRQIRV GNTPETRGTA YVV
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 95%.
Target Information
SF3B14 encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: pre mRNA branch site protein p14; Pre-mRNA branch site protein p14; SF3b 14 kDa subunit; SF3B14a; spliceosome-associated protein, 14 kDa subunit; Spliceosome-associated protein, 14-kDa; Splicing factor 3B subunit 6; splicing factor 3B, 14 kDa subunit; Splicing factor 3b, subunit 6, 14kDa
Gene Aliases: CGI-110; HSPC175; HT006; P14; SAP14; SAP14a; SF3B14; SF3B14A; SF3B6
UniProt ID: (Human) Q9Y3B4
Entrez Gene ID: (Human) 51639
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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