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SFTPA1/SFTPA2 Antibody (PA5-38059) in IHC (P)
Immunohistochemistry analysis of SFTPA1/SFTPA2 in human lung. Samples were incubated with SFTPA1/SFTPA2 polyclonal antibody (Product # PA5-38059) using a dilution of 5 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Product Details
PA5-38059
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-HLDEELQATLHDFR, from the internal region of SFTPA1 (aa102-115)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2554663
Product Specific Information
This antibody is predicted to react with cow based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
Surfactant protein A (SP-A) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-D and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is 45 ng/mL in healthy individuals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 35 kDa pulmonary surfactant-associated protein; Alveolar proteinosis protein; collectin 5; Collectin-4; Collectin-5; FLJ50593; FLJ51913; FLJ61144; FLJ77898; FLJ79095; FLJ99559; MGC133365; MGC198590; PSP-A; Pulmonary surfactant-associated protein A1; Pulmonary surfactant-associated protein A2; SP-2A beta; SP-2A gamma; SP-A1 beta; SP-A1 delta; SP-A1 epsilon; SP-A1 gamma; SP-A2; SP-A2 alpha; SP-A2 delta; surfactant protein A1 variant AB'D' 6A; surfactant protein A1 variant AB'D' 6A2; surfactant protein A1 variant AB'D' 6A3; surfactant protein A1 variant AB'D' 6A4; surfactant protein A1 variant ACD' 6A; surfactant protein A1 variant ACD' 6A2; surfactant protein A1 variant ACD' 6A3; surfactant protein A1 variant ACD' 6A4; surfactant protein A1 variant AD' 6A; surfactant protein A1 variant AD' 6A2; surfactant protein A1 variant AD' 6A3; surfactant protein A1 variant AD' 6A4; surfactant protein A1B; surfactant, pulmonary-associated protein A1A; surfactant, pulmonary-associated protein A1B; surfactant, pulmonary-associated protein A2A
Gene Aliases: COLEC4; COLEC5; PSAP; PSP-A; PSPA; SFTP1; SFTPA; SFTPA1; SFTPA1B; SFTPA2; SFTPA2B; SP-2A; SP-A; SP-A1; SPA; SPA1; SPA2; SPAII
UniProt ID: (Human) Q8IWL2, (Human) Q8IWL1
Entrez Gene ID: (Human) 653509, (Human) 729238
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