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Invitrogen
SFTPA1/SFTPA2 Polyclonal Antibody
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SFTPA1/SFTPA2 Antibody (PA5-79987) in IHC (P)
Immunohistochemistry (Paraffin) analysis of SFTPA1/SFTPA2 in paraffin-embedded section of rat lung tissue using SFTPA1/SFTPA2 Polyclonal Antibody (Product # PA5-79987). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 5 µg/mL dilution over... View More
Product Details
PA5-79987
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human SFTPA1/2 (206-237aa VNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRN).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2747102
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat lung tissue, mouse lung tissue. IHC: Mouse Lung tissue, Rat Lung tissue, Human Lung Cancer tissue IHC-F: Mouse Lung tissue, Rat Lung tissue.
Target Information
Surfactant protein A (SP-A) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-D and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is 45 ng/mL in healthy individuals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 35 kDa pulmonary surfactant-associated protein; Alveolar proteinosis protein; collectin 5; Collectin-4; Collectin-5; FLJ50593; FLJ51913; FLJ61144; FLJ77898; FLJ79095; FLJ99559; MGC133365; MGC198590; PSAP; PSP-A; Pulmonary surfactant-associated protein A; Pulmonary surfactant-associated protein A1; Pulmonary surfactant-associated protein A2; SP-2A beta; SP-2A gamma; SP-A1 beta; SP-A1 delta; SP-A1 epsilon; SP-A1 gamma; SP-A2; SP-A2 alpha; SP-A2 delta; surfactant associated protein A; surfactant protein A1 variant AB'D' 6A; surfactant protein A1 variant AB'D' 6A2; surfactant protein A1 variant AB'D' 6A3; surfactant protein A1 variant AB'D' 6A4; surfactant protein A1 variant ACD' 6A; surfactant protein A1 variant ACD' 6A2; surfactant protein A1 variant ACD' 6A3; surfactant protein A1 variant ACD' 6A4; surfactant protein A1 variant AD' 6A; surfactant protein A1 variant AD' 6A2; surfactant protein A1 variant AD' 6A3; surfactant protein A1 variant AD' 6A4; surfactant protein A1B; surfactant pulmonary associated protein A1; surfactant, pulmonary-associated protein A1; surfactant, pulmonary-associated protein A1A; surfactant, pulmonary-associated protein A1B; surfactant, pulmonary-associated protein A2A; Surfactant-associated protein 1 (pulmonary surfactant protein SP-A); Surfactant-associated protein 1 (pulmonary surfactant protein, SP-A)
Gene Aliases: COLEC4; COLEC5; PSAP; PSP-A; PSPA; Sftp-1; SFTP1; SFTPA; SFTPA1; SFTPA1B; SFTPA2; SFTPA2B; Sftpl; SP-2A; SP-A; SP-A1; SPA; SPA1; SPA2; SPAII
UniProt ID: (Human) Q8IWL2, (Human) Q8IWL1, (Rat) P08427
Entrez Gene ID: (Human) 653509, (Human) 729238, (Rat) 24773, (Mouse) 20387
lipid transport
respiratory gaseous exchange
cellular protein metabolic process
response to hypoxia
circadian rhythm
response to hormone
response to lipopolysaccharide
response to retinoic acid
response to vitamin A
positive regulation of phagocytosis
response to glucocorticoid
response to hyperoxia
response to interleukin-6
response to epidermal growth factor
cellular response to mechanical stimulus
cellular response to nitric oxide
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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