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Proteintech
SFTPB Polyclonal Antibody
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Product Details
13664-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SFTPB Fusion Protein Ag4576 (1-381 aa encoded by BC032785)
Conjugate
Form
Liquid
Concentration
0.16 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAESHLLQW LLLLLPTLCG PGTAAWTTSS LACAQGPEFW CQSLEQALQC RALGHCLQEV WGHVGADDLC QECEDIVHIL NKMAKEAIFQ DTMRKFLEQE CNVLPLKLLM PQCNQVLDDY FPLVIDYFQN QTDSNGICMH LGLCKSRQPE PEQEPGMSDP LPKPLRDPLP DPLLDKLVLP VLPGALQARP GPHTQDLSEQ QFPIPLPYCW LCRALIKRIQ AMIPKGALAV AVAQVCRVVP LVAGGICQCL AERYSVILLD TLLGRMLPQL VCRLVLRCSM DDSAGPRSPT GEWLPRDSEC HLCMSVTTQA GNSSEQAIPQ AMLQACVGSW LDREKCKQFV EQHTPQLLTL VPRGWDAHTT CQALGVCGTM SSPLQCIHSP DL (1-381 aa encoded by BC032785)
Target Information
Pulmonary surfactant is a complex mixture of phospholipids and proteins that is secreted from type II cells in alveoli and reduces the surface tension at the alveolar air-liquid interface, providing alveolar stability necessary for normal ventilation. Four distinct proteins isolated from pulmonary surfactant are termed surfactant proteins A, B, C, and D. SP-A (28-36kDa) and SP-D (43kDa) are collagenous carbohydrate-binding proteins, whereas SP-B (8-9kDa) and SP-C (4kDa) are non-collagenous hydrophobic proteins. SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns. Squamous cell and large cell carcinomas of the lung and nonpulmonary adenocarcinomas do not express SP-B. ProSP-B is glycosylated in the Golgi apparatus and undergoes carboxy- and amino-terminal proteolysis by a cathepsin D-like protease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 18 kDa pulmonary-surfactant protein; 6 kDa protein; P SFTB3; Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteolipid SPL(Phe); SFPB; SP-B
Gene Aliases: PSP-B; SFTB3; SFTP3; SFTPB; SMDP1; SP-B
UniProt ID: (Human) P07988
Entrez Gene ID: (Human) 6439
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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