Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MESKMGELP LDINIQEPRW DQSTFLGRAR HFFTVTDPRN LLLSGAQLEA SRNIVQNYRA GVVTPGITED QLWRAKYVYD SAFHPDTGEK VVLIGRMSAQ VPMNMTITGC MLTFYRKTPT VVFWQWVNQS FNAIVNYSNR SGDTP (1-144 aa encoded by BC000124)
Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. Also catalyzes an electroneutral exchange of tricarboxylate, dicarboxylate, or phosphoenolpyruvate across the mitochondrial inner membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Sideroflexin-3; tricarboxylate carrier; tricarboxylate carrier-like protein
Gene Aliases: BA108L7.2; SFX3; SFXN3; TCC
UniProt ID: (Human) Q9BWM7, (Rat) Q9JHY2, (Mouse) Q91V61
Entrez Gene ID: (Human) 81855, (Rat) 65042, (Mouse) 94280
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