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FIGURE: 1 / 1
Sequence of this protein is as follows: MESKMGELPL DINIQEPRWD QSTFLGRARH FFTVTDPRNL LLSGAQLEAS RNIVQNYRAG VVTPGITEDQ LWRAKYVYDS AFHPDTGEKV VLIGRMSAQV PMNMTITGCM LTFYRKTPTV VFWQWVNQSF NAIVNYSNRS GDTPITVRQL GTAYVSATTG AVATALGLKS LTKHLPPLVG RFVPFAAVAA ANCINIPLMR QRELQVGIPV ADEAGQRLGY SVTAAKQGIF QVVISRICMA IPAMAIPPLI MDTLEKKDFL KRRPWLGAPL QVGLVGFCLV FATPLCCALF PQKSSIHISN LEPELRAQIH EQNPSVEVVY YNKGL
Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. Also catalyzes an electroneutral exchange of tricarboxylate, dicarboxylate, or phosphoenolpyruvate across the mitochondrial inner membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Sideroflexin-3
Gene Aliases: BA108L7.2; SFX3; SFXN3
UniProt ID: (Human) Q9BWM7
Entrez Gene ID: (Human) 81855
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