Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: NLRVTKKGIR LEGISEFLLP LYVKEIHSRK DSPLVLQSDR NVTVNARNHM GQLTGQLTIG ADAVEAQCKR FEVRASEDGR VLFSADEDEI TIGAEKLKVT GTEGAVFGHS VETPHIRAEP SQDLRLESPT RSLIMEAPRG VQVSAAAGDF KATCRKELHL QSTEGEIFLN AETIKLGNLP TGSFSSSSPS SSSSRQTVYE LCVCPNGKLY LSPAGVGSTC QSSSNICLWS
The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix.
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Protein Aliases: sarcoglycan, zeta; Zeta-sarcoglycan; Zeta-SG; ZSG1
Gene Aliases: C230085N17Rik; SGCZ; ZSG1
UniProt ID: (Human) Q96LD1, (Mouse) Q8BX51
Entrez Gene ID: (Human) 137868, (Mouse) 244431, (Rat) 364605
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