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Product Details
H00010110-M08
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
7C7
Immunogen
SGK2 (AAH65511, 293 a.a. approximately 367 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: SPINWDDLYH KRLTPPFNPN VTGPADLKHF DPEFTQEAVS KSIGCTPDTV ASSSGASSAF LGFSYAPEDD DILDC
Target Information
SGK2 is a serine/threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGK2 is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Although little is known about the transcriptional regulation of SGK2, the protein has been shown to be phosphorylated and activated by 3 phosphoinositide dependent protein kinase 1 (PDK1), and to a lesser extent insulin like growth factor 1, in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Serine/threonine-protein kinase Sgk2; serum/glucocorticoid regulated kinase 2; Serum/glucocorticoid-regulated kinase 2
Gene Aliases: dJ138B7.2; H-SGK2; SGK2
UniProt ID: (Human) Q9HBY8
Entrez Gene ID: (Human) 10110
regulation of cell growth
protein phosphorylation
cellular sodium ion homeostasis
response to oxidative stress
positive regulation of sodium ion transport
peptidyl-serine phosphorylation
positive regulation of transporter activity
ion transmembrane transport
intracellular signal transduction
regulation of cell proliferation
regulation of apoptotic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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