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Recommended positive controls: HepG2.
Predicted reactivity: Mouse (96%), Zebrafish (82%), Dog (99%), Chicken (95%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
SGKL (SGK3) is a serine/threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGKL is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytokine-independent survival kinase; DKFZp781N0293; Serine/threonine-protein kinase Sgk3; Serum/glucocorticoid-regulated kinase 3; Serum/glucocorticoid-regulated kinase-like
Gene Aliases: CISK; SGK2; SGK3; SGKL
UniProt ID: (Human) Q96BR1
Entrez Gene ID: (Human) 23678
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