Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
SH2D1B Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 2
SH2D1B Antibody (PA5-106376) in IHC (P)
Immunohistochemistry analysis of SH2D1B in mouse heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with SH2D1B polyclonal antibody (Product # PA5-106376) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-106376
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SH2D1B(Accession O14796), corresponding to amino acid residues K85-P132.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2854051
Product Specific Information
Antibody detects endogenous levels of total SH2D1B.
Target Information
SH2D1B plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: EAT-2; EWS/FLI1 activated transcript 2; EWS/FLI1-activated transcript 2; SH2 domain containing 1B; SH2 domain protein 1B1; SH2 domain-containing molecule EAT2; SH2 domain-containing protein 1B
Gene Aliases: EAT-2; EAT-2A; EAT2; Eat2a; RGD1563935; SH2D1B; Sh2d1b1
UniProt ID: (Human) O14796
Entrez Gene ID: (Human) 117157, (Rat) 501869, (Mouse) 26904
adaptive immune response
leukocyte activation involved in immune response
positive regulation of natural killer cell mediated immunity
innate immune response
positive regulation of innate immune response
regulation of immune response
natural killer cell inhibitory signaling pathway
positive regulation of signal transduction
peptidyl-tyrosine phosphorylation
negative regulation of interferon-gamma production
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of peptidyl-tyrosine phosphorylation
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support