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Proteintech
SH3BP5 Monoclonal Antibody (1B9D4), CoraLite® Plus 488
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FIGURE: 1 / 1
SH3BP5 Antibody (CL488-67841) in Flow
1X10^6 HeLa cells were intracellularly stained with 0.4 µg CoraLite® Plus 488 Anti-Human SH3BP5 (CL488-67841, Clone:1B9D4) (red), or 0.4 µg Control Antibody. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Product Details
CL488-67841
Product Specifications
Species Reactivity
Chicken,
Human,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1B9D4
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: EKLNQSTDDI NRRETELEDA RQKFRSVLVE ATVKLDELVK KIGKAVEDSK PYWEARRVAR QAQLEAQKAT QDFQRATEVL RAAKETISLA EQRLLEDDKR QFDSAWQEML NHATQRVMEA EQTKTRSELV HKETAARYNA AMGRMRQLEK KLKRAINKSK PYFELKAKYY VQLEQLKKTV DDLQAKLTLA KGEYKMALKN LEMISDEIHE RRRSSAMGPR GCGVGAEGSS TSVEDLPGSK PEPDAISVAS EAFEDDSCSN FVSEDDSETQ SVSSFSSGPT SPSEMPDQFP AVVRPGSLDL PSPVSLSEFG MMFPVLGPRS ECSGASSPEC EVERGDRAEG AENKTSDKAN NNRGLSSSSG SGGSSKSQSS TSPEGQALEN RMKQLSLQCS KGRDGIIADI KMVQIG
Target Information
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SH3 binding protein; SH3 domain-binding protein 5; SH3 domain-binding protein that preferentially associates with BTK; SH3-domain binding protein 5 (BTK-associated); SH3BP-5; Vascular endothelial cell-specific protein 18
Gene Aliases: AI606498; RCJMB04_13o18; SAB; SH3BP-5; SH3BP5; Vesp18
UniProt ID: (Human) O60239, (Rat) Q91Y80, (Mouse) Q9Z131
Entrez Gene ID: (Rabbit) 100339405, (Human) 9467, (Chicken) 420682, (Rat) 117186, (Mouse) 24056
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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