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Proteintech
SHKBP1 Polyclonal Antibody
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Product Details
12703-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SHKBP1 Fusion Protein Ag3386 (358-707 aa encoded by BC022855)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKDNDLLVS ELYRDPAEDG VTALSVYLTP KTSDSGNWIE IAYGTSSGGV RVIVQHPETV GSGPQLFQTF TVHRSPVTKI MLSEKHLISV CADNNHVRTW SVTRFRGMIS TQPGSTPLAS FKILALESAD GHGGCSAGND IGPYGERDDQ LVFIQKVVPS ASQLFVRLSS TGQRVCSVRS VDGSPTTAFT VLECEGSRRL GSRPRRYLLT GQANGSLAMW DLTTAMDGLG QAPAGGLTEQ ELMEQLEHCE LAPPAPSAPS WGCLPSPSPR ISLTSLHSAS SNTSLSGHRG SPSPPQAEAR RRGGGSFVER CQELVRSGPD LRRPPTPAPW PSSGLGTPLT PPKMKLNETS F (358-707 aa encoded by BC022855)
Target Information
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SETA binding protein 1; SETA-binding protein 1; SH3KBP1-binding protein 1
Gene Aliases: B930062H15Rik; PP203; RGD1309281; SB1; SHKBP1
UniProt ID: (Human) Q8TBC3, (Rat) P0C5J9, (Mouse) Q6P7W2
Entrez Gene ID: (Human) 92799, (Rat) 292735, (Mouse) 192192
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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