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Bethyl Laboratories
SHPK Polyclonal Antibody
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SHPK Antibody (A305-719A-T) in IP
Detection of human SHPK by western blot of immunoprecipitates. Samples: Whole cell lysate (1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-SHPK antibody A305-719A-M (lot A305-719A-M-1) used for IP at 8 µl per reaction. SHPK was also immunoprecipitated by rabbit anti-SHPK antibody BL22963. For blotting immunoprecipitated SHPK, A305-719A-M was used at 1:400. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A305-719A-T
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A region between residue 350 to 400 of human Sedoheptulokinase.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7.0 to 8.0
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Wet ice
Product Specific Information
Predicted reactivity by homology: Mouse.
Target Information
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Carbohydrate kinase-like protein; Sedoheptulokinase; SHK
Gene Aliases: CARKL; SHK; SHPK
UniProt ID: (Human) Q9UHJ6
Entrez Gene ID: (Human) 23729
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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