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Product Details
H00057619-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SHROOM3 (AAI56133.1, 1 a.a. approximately 1995 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MRTTEDFHKP SATLNSNTAT KGRYIYLEAF LEGGAPWGFT LKGGLEHGEP LIISKVEEGG KADTLSSKLQ AGDEVVHINE VTLSSSRKEA VSLVKGSYKT LRLVVRRDVC TDPGHADTGA SNFVSPEHLT SGPQHRKAAW SGGVKLRLKH RRSEPAGRPH SWHTTKSGEK QPDASMMQIS QGMIGPPWHQ SYHSSSSTSD LSNYDHAYLR RSPDQCSSQG SMESLEPSGA YPPCHLSPAK STGSIDQLSH FHNKRDSAYS SFSTSSSILE YPHPGISGRE RSGSMDNTSA RGGLLEGMRQ ADIRYVKTVY DTRRGVSAEY EVNSSALLLQ GREARASANG QGYDKWSNIP RGKGVPPPSW SQQCPSSLET ATDNLPPKVG APLPPARSDS YAAFRHRERP SSWSSLDQKR LCRPQANSLG SLKSPFIEEQ LHTVLEKSPE NSPPVKPKHN YTQKAQPGQP LLPTSIYPVP SLEPHFAQVP QPSVSSNGML YPALAKESGY IAPQGACNKM ATIDENGNQN GSGRPGFAFC QPLEHDLLSP VEKKPEATAK YVPSKVHFCS VPENEEDASL KRHLTPPQGN SPHSNERKST HSNKPSSHPH SLKCPQAQAW QAGEDKRSSR LSEPWEGDFQ EDHNANLWRR LEREGLGQSL SGNFGKTKSA FSSLQNIPES LRRHSSLELG RGTQEGYPGG RPTCAVNTKA EDPGRKAAPD LGSHLDRQVS YPRPEGRTGA SASFNSTDPS PEEPPAPSHP HTSSLGRRGP GPGSASALQG FQYGKPHCSV LEKVSKFEQR EQGSQRPSVG GSGFGHNYRP HRTVSTSSTS GNDFEETKAH IRFSESAEPL GNGEQHFKNG ELKLEEASRQ PCGQQLSGGA SDSGRGPQRP DARLLRSQST FQLSSEPERE PEWRDRPGSP ESPLLDAPFS RAYRNSIKDA QSRVLGATSF RRRDLELGAP VASRSWRPRP SSAHVGLRSP EASASASPHT PRERHSVTPA EGDLARPVPP AARRGARRRL TPEQKKRSYS EPEKMNEVGI VEEAEPAPLG PQRNGMRFPE SSVADRRRLF ERDGKACSTL SLSGPELKQF QQSALADYIQ RKTGKRPTSA AGCSLQEPGP LRERAQSAYL QPGPAALEGS GLASASSLSS LREPSLQPRR EATLLPATVA ETQQAPRDRS SSFAGGRRLG ERRRGDLLSG ANGGTRGTQR GDETPREPSS WGARAGKSMS AEDLLERSDV LAGPVHVRSR SSPATADKRQ DVLLGQDSGF GLVKDPCYLA GPGSRSLSCS ERGQEEMLPL FHHLTPRWGG SGCKAIGDSS VPSECPGTLD HQRQASRTPC PRPPLAGTQG LVTDTRAAPL TPIGTPLPSA IPSGYCSQDG QTGRQPLPPY TPAMMHRSNG HTLTQPPGPR GCEGDGPEHG VEEGTRKRVS LPQWPPPSRA KWAHAAREDS LPEESSAPDF ANLKHYQKQQ SLPSLCSTSD PDTPLGAPST PGRISLRISE SVLRDSPPPH EDYEDEVFVR DPHPKATSSP TFEPLPPPPP PPPSQETPVY SMDDFPPPPP HTVCEAQLDS EDPEGPRPSF NKLSKVTIAR ERHMPGAAHV VGSQTLASRL QTSIKGSEAE STPPSFMSVH AQLAGSLGGQ PAPIQTQSLS HDPVSGTQGL EKKVSPDPQK SSEDIRTEAL AKEIVHQDKS LADILDPDSR LKTTMDLMEG LFPRDVNLLK ENSVKRKAIQ RTVSSSGCEG KRNEDKEAVS MLVNCPAYYS VSAPKAELLN KIKEMPAEVN EEEEQADVNE KKAELIGSLT HKLETLQEAK GSLLTDIKLN NALGEEVEAL ISELCKPNEF DKYRMFIGDL DKVVNLLLSL SGRLARVENV LSGLGEDASN EERSSLYEKR KILAGQHEDA RELKENLDRR ERVVLGILAN YLSEEQLQDY QHFVKMKSTL LIEQRKLDDK IKLGQEQVKC LLESLPSDFI PKAGALALPP NLTSEPIPAG GCTFSGIFPT LTSPL
Target Information
SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM3 is an actin-binding protein is a regulator of the microtubule cytoskeleton during epithelial morphogenesis and is sufficient and necessary to induce a redistribution of the microtubule regulator gamma-tubulin. It is necessary for both apiscobasal cell elongation and apical constriction in the neural epithelium. SHROOM3 has also been shown to be essential for cell shape changes and morphogenesis in the developing vertebrate gut, with its transcription relying on the Pitx1 transcription factor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: F-actin-binding; F-actin-binding protein; hShrmL; Protein Shroom3; Shroom-related protein
Gene Aliases: APXL3; KIAA1481; MSTP013; SHRM; SHRML; SHROOM3
UniProt ID: (Human) Q8TF72
Entrez Gene ID: (Human) 57619
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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