Product References
Dynamic change in Siglec-15 expression in peritumoral macrophages confers an immunosuppressive microenvironment and poor outcome in glioma.
Frontiers in immunology
Chen Q,Chen B,Wang C,Hu L,Wu Q,Zhu Y,Zhang Q
PA5-72765 was used in Immunohistochemistry-immunofluorescence to identify dynamic changes in Siglec-15 expression and distribution in human glioma tissues, indicating that the timing of Siglec-15 blockade is critical to achieve an effective combination with other immune checkpoint inhibitors in clinical practice.
Mon May 29 00:00:00 UTC 2023
Dynamic change in Siglec-15 expression in peritumoral macrophages confers an immunosuppressive microenvironment and poor outcome in glioma.
Frontiers in immunology
Chen Q,Chen B,Wang C,Hu L,Wu Q,Zhu Y,Zhang Q
PA5-72765 was used in Immunohistochemistry-immunofluorescence to identify dynamic changes in Siglec-15 expression and distribution in human glioma tissues, indicating that the timing of Siglec-15 blockade is critical to achieve an effective combination with other immune checkpoint inhibitors in clinical practice.
Mon May 29 00:00:00 UTC 2023
Transcriptional Regulation of Siglec-15 by ETS-1 and ETS-2 in Hepatocellular Carcinoma Cells.
International journal of molecular sciences
Sheng K,Wu Y,Lin H,Fang M,Xue C,Lin X,Lin X
PA5-72765 was used in ELISA, Immunohistochemistry (Paraffin), Western Blot, Flow Cytometry to define a detailed molecular profile of how Siglec-15 is transcriptionally regulated which may offer significant opportunity for therapeutic intervention on HCC immunotherapy.
Mon Jan 02 00:00:00 UTC 2023
Transcriptional Regulation of Siglec-15 by ETS-1 and ETS-2 in Hepatocellular Carcinoma Cells.
International journal of molecular sciences
Sheng K,Wu Y,Lin H,Fang M,Xue C,Lin X,Lin X
PA5-72765 was used in ELISA, Immunohistochemistry (Paraffin), Western Blot, Flow Cytometry to define a detailed molecular profile of how Siglec-15 is transcriptionally regulated which may offer significant opportunity for therapeutic intervention on HCC immunotherapy.
Mon Jan 02 00:00:00 UTC 2023
Significance of Siglec-15 expression in colorectal cancer: association with advanced disease stage and fewer tumor-infiltrating lymphocytes.
The journal of pathology. Clinical research
Lu Z,Cheng P,Huang F,Li J,Wang B,Zou S,Zheng Z,Peng C
PA5-72765 was used in Immunohistochemistry to explore the expression of Siglec-15 in colorectal cancer (CRC), and investigate whether Siglec-15 could be a potential target for cancer immunotherapy in patients with colorectal cancer.
Wed Mar 01 00:00:00 UTC 2023
Sialic acid-binding immunoglobulin-like lectin-15 expression on peritumoral macrophages is a favorable prognostic factor for primary central nervous system lymphoma patients.
Scientific reports
Fudaba H,Momii Y,Hirakawa T,Onishi K,Asou D,Matsushita W,Kawasaki Y,Sugita K,Fujiki M
PA5-72765 was used in Immunohistochemistry to indicate that the expression of Siglec-15 on peritumoral macrophages induces a favorable outcome in PCNSL patients.
Wed Jan 13 00:00:00 UTC 2021
Sialic acid-binding immunoglobulin-like lectin-15 expression on peritumoral macrophages is a favorable prognostic factor for primary central nervous system lymphoma patients.
Scientific reports
Fudaba H,Momii Y,Hirakawa T,Onishi K,Asou D,Matsushita W,Kawasaki Y,Sugita K,Fujiki M
PA5-72765 was used in Immunohistochemistry to indicate that the expression of Siglec-15 on peritumoral macrophages induces a favorable outcome in PCNSL patients.
Wed Jan 13 00:00:00 UTC 2021
Sialic acid-binding immunoglobulin-like lectin-15 expression on peritumoral macrophages is a favorable prognostic factor for primary central nervous system lymphoma patients.
Scientific reports
Fudaba H,Momii Y,Hirakawa T,Onishi K,Asou D,Matsushita W,Kawasaki Y,Sugita K,Fujiki M
PA5-72765 was used in Immunohistochemistry to indicate that the expression of Siglec-15 on peritumoral macrophages induces a favorable outcome in PCNSL patients.
Wed Jan 13 00:00:00 UTC 2021
Gene Expression Profiles Analyzed Using Integrating RNA Sequencing, and Microarray Reveals Increased Inflammatory Response, Proliferation, and Osteoclastogenesis in Pigmented Villonodular Synovitis.
Frontiers in immunology
Zhao Y,Lv J,Zhang H,Xie J,Dai H,Zhang X
PA5-72765 was used in Immunohistochemistry (Paraffin) to analyse gene expression profiles of six patients with PVNS, 11 patients with osteoarthritis (OA), nine patients with rheumatoid arthritis (RA) (E-MTAB-6141), and three healthy subjects (GSE143514).
Mon Oct 25 00:00:00 UTC 2021
Gene Expression Profiles Analyzed Using Integrating RNA Sequencing, and Microarray Reveals Increased Inflammatory Response, Proliferation, and Osteoclastogenesis in Pigmented Villonodular Synovitis.
Frontiers in immunology
Zhao Y,Lv J,Zhang H,Xie J,Dai H,Zhang X
PA5-72765 was used in Immunohistochemistry (Paraffin) to analyse gene expression profiles of six patients with PVNS, 11 patients with osteoarthritis (OA), nine patients with rheumatoid arthritis (RA) (E-MTAB-6141), and three healthy subjects (GSE143514).
Mon Oct 25 00:00:00 UTC 2021
The significance of Siglec-15 expression in resectable non-small cell lung cancer.
Neoplasma
Hao JQ,Nong JY,Zhao D,Li HY,Su D,Zhou LJ,Dong YJ,Zhang C,Che NY,Zhang SC,Lin JZ,Yang JB,Zhang HT,Wang JH
PA5-72765 was used in Immunohistochemistry to investigate the significance of S15 expression with the clinicopathological and prognosis of patients with NSCLC and TILs.
Sun Nov 01 00:00:00 UTC 2020
Expression signature, prognosis value, and immune characteristics of Siglec-15 identified by pan-cancer analysis.
Oncoimmunology
Li B,Zhang B,Wang X,Zeng Z,Huang Z,Zhang L,Wei F,Ren X,Yang L
PA5-72765 was used in Immunohistochemistry to understand Siglec-15 expression signature, prognosis value, immune infiltration pattern, and biological function using multi-omic bioinformatics from public databases and verify them in lung cancer patients.
Fri Aug 28 00:00:00 UTC 2020
Expression signature, prognosis value, and immune characteristics of Siglec-15 identified by pan-cancer analysis.
Oncoimmunology
Li B,Zhang B,Wang X,Zeng Z,Huang Z,Zhang L,Wei F,Ren X,Yang L
PA5-72765 was used in Immunohistochemistry to understand Siglec-15 expression signature, prognosis value, immune infiltration pattern, and biological function using multi-omic bioinformatics from public databases and verify them in lung cancer patients.
Fri Aug 28 00:00:00 UTC 2020
