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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SIX2 Antibodies

          Proteintech

          SIX2 Polyclonal Antibody

          267 References
          View all (12) SIX2 antibodies
          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite SIX2 Polyclonal Antibody

          • Antibody Testing Data (7)
          SIX2 Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.
          SIX2 Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          SIX2 Antibody (11562-1-AP) in IHC

          IF result from Fogelgren B, PMID:18570229, "Misexpression of Six2 is associated with heritable frontonasal dysplasia and renal hypoplasia in 3H1 Br mice.". {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          SIX2 Antibody in Immunohistochemistry (IHC)
          SIX2 Antibody in Western Blot (WB)
          SIX2 Antibody in Western Blot (WB)
          SIX2 Antibody in Western Blot (WB)
          SIX2 Antibody in Western Blot (WB)
          SIX2 Antibody in Immunoprecipitation (IP)
          SIX2 Antibody in Immunoprecipitation (IP)

          Product Details

          11562-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 27 publications 27 publications

          Immunohistochemistry (IHC)

          -
          View 35 publications 35 publications

          Immunocytochemistry (ICC/IF)

          -
          View 193 publications 193 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 3 publications 3 publications

          ChIP assay (ChIP)

          Assay-dependent
          View 5 publications 5 publications

          Miscellaneous PubMed (MISC)

          -
          View 1 publication 1 publication

          Not applicable (N/A)

          -
          View 3 publications 3 publications
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human, Mouse, Pig, Rat, Reptile

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          SIX2 Fusion Protein Ag2124 (1-291 aa encoded by BC024033)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.52 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          This antibody is a rabbit polyclonal antibody raised against full length SIX2 of human origin.

          Immunogen sequence: MSMLPTFGF TQEQVACVCE VLQQGGNIER LGRFLWSLPA CEHLHKNESV LKAKAVVAFH RGNFRELYKI LESHQFSPHN HAKLQQLWLK AHYIEAEKLR GRPLGAVGKY RVRRKFPLPR SIWDGEETSY CFKEKSRSVL REWYAHNPYP SPREKRELTE ATGLTTTQVS NWFKNRRQRD RAAEAKEREN NENSNSNSHN PLNGSGKSVL GSSEDEKTPS GTPDHSSSSP ALLLSPPPPG LPSLHSLGHP PGPSAVPVPV PGGGGADPLQ HHHGLQDSIL NPMSANLVDL GS (1-291 aa encoded by BC024033)

          Target Information

          This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. SIX2 is a transcription factor which, like other members of this gene family, may be involved in limb or eye development.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Homeobox protein SIX2; Sine oculis homeobox homolog 2

          View more View less

          Gene Aliases: SIX2

          View more View less

          UniProt ID: (Human) Q9NPC8

          View more View less

          Entrez Gene ID: (Human) 10736

          View more View less

          Function(s)
          RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding transcription factor binding protein complex binding
          Process(es)
          kidney development chondrocyte differentiation mesenchymal to epithelial transition involved in metanephros morphogenesis transcription from RNA polymerase II promoter protein import into nucleus mesodermal cell fate specification cell proliferation anatomical structure morphogenesis anterior/posterior axis specification cell migration regulation of ossification regulation of chondrocyte differentiation middle ear morphogenesis negative regulation of cell differentiation positive regulation of transcription from RNA polymerase II promoter embryonic digestive tract morphogenesis embryonic cranial skeleton morphogenesis nephron development nephron morphogenesis mesenchymal stem cell maintenance involved in nephron morphogenesis mesenchymal cell differentiation involved in kidney development regulation of branching involved in ureteric bud morphogenesis mesenchymal stem cell proliferation positive regulation of chondrocyte proliferation
          It has to be done as per old AB suggested Products section.
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