Proteintech

SKAR Polyclonal Antibody

SKAR Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 6

SKAR Antibody (17466-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 17466-1-AP (SKAR antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

SKAR Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

17466-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SKAR Fusion Protein Ag11338 (1-229 aa encoded by BC019643)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.36 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MADISLDEL IRKRGAAAKG RLNARPGVGG VRSRVGIQQG LLSQSTRTAT FQQRFDARQK IGLSDARLKL GVKDAREKLL QKDARFRIKG KVQDAREMLN SRKQQTTVPQ KPRQVADARE KISLKRSSPA AFINPPIGTV TPALKLTKTI QNLYDLDEDD DGIASVPTKQ MKFAASGGFL HHMAGLSSSK LSMSKALPLT KVVQNDAYTA PALPSSIRTK ALPVLTSPGT (1-229 aa encoded by BC019643)

Target Information

This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Inhibition of mTORC1 signaling sensitizes hepatocellular carcinoma cells to glycolytic stress.

American journal of cancer research

Zhao X,Jiang P,Deng X,Li Z,Tian F,Guo F,Li X,Wang S

Sat Apr 09 00:00:00 UTC 2022

Inhibition of mTORC1 signaling sensitizes hepatocellular carcinoma cells to glycolytic stress.

American journal of cancer research

Zhao X,Jiang P,Deng X,Li Z,Tian F,Guo F,Li X,Wang S

Sat Apr 09 00:00:00 UTC 2022

PDIP46 (DNA polymerase δ interacting protein 46) is an activating factor for human DNA polymerase δ.

Oncotarget

Wang X,Zhang S,Zheng R,Yue F,Lin SH,Rahmeh AA,Lee EY,Zhang Z,Lee MY

Tue Feb 02 00:00:00 UTC 2016

PDIP46 (DNA polymerase δ interacting protein 46) is an activating factor for human DNA polymerase δ.

Oncotarget

Wang X,Zhang S,Zheng R,Yue F,Lin SH,Rahmeh AA,Lee EY,Zhang Z,Lee MY

Tue Feb 02 00:00:00 UTC 2016

TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.

Scientific reports

Prpar Mihevc S,Baralle M,Buratti E,Rogelj B

Mon Sep 26 00:00:00 UTC 2016

TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.

Scientific reports

Prpar Mihevc S,Baralle M,Buratti E,Rogelj B

Mon Sep 26 00:00:00 UTC 2016

TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.

Scientific reports

Prpar Mihevc S,Baralle M,Buratti E,Rogelj B

Mon Sep 26 00:00:00 UTC 2016

TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.

Scientific reports

Prpar Mihevc S,Baralle M,Buratti E,Rogelj B

Mon Sep 26 00:00:00 UTC 2016

Bioinformatics

Protein Aliases: 46 kDa DNA polymerase delta interaction protein; p46; polymerase (DNA) delta interacting protein 3; polymerase (DNA-directed), delta interacting protein 3; polymerase delta interacting protein 46; Polymerase delta-interacting protein 3; RNA-binding protein P46; S6K1 Aly/REF-like target; SKAR

View more View less

Gene Aliases: 1110008P04Rik; AA408269; AL022852; C77954; KIAA1649; mKIAA1649; PDIP46; POLDIP3; SKAR

View more View less

UniProt ID: (Human) Q9BY77, (Mouse) Q8BG81

View more View less

Entrez Gene ID: (Human) 84271, (Mouse) 73826, (Rat) 315170

View more View less

Function(s)

nucleotide binding protein binding poly(A) RNA binding nucleic acid binding RNA binding

Process(es)

termination of RNA polymerase II transcription RNA export from nucleus mRNA export from nucleus poly(A)+ mRNA export from nucleus mRNA 3'-end processing positive regulation of translation regulation of translation transport mRNA transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

SKAR Polyclonal Antibody

SKAR Antibody (17466-1-AP) in ICC/IF

Product Details

17466-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!