Proteintech

SKIV2L2 Polyclonal Antibody

FIGURE: 1 / 6

SKIV2L2 Antibody (12719-2-AP) in WB

Mouse testis tissue were subjected to SDS PAGE followed by western blot with 12719-2-AP (SKIV2L2 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours.

SKIV2L2 Antibody in Immunoprecipitation (IP)

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Product Details

12719-2-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:8,000

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

Assay-dependent

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SKIV2L2 Fusion Protein Ag3414 (3-307 aa encoded by BC028604)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: DAFGDELFS VFEGDSTTAA GTKKDKEKDK GKWKGPPGSA DKAGKRFDGK LQSESTNNGK NKRDVDFEGT DEPIFGKKPR IEESITEDLS LADLMPRVKV QSVETVEGCT HEVALPAEED YLPLKPRVGK AAKEYPFILD AFQREAIQCV DNNQSVLVSA HTSAGKTVCA EYAIALALRE KQRVIFTSPI KALSNQKYRE MYEEFQDVGL MTGDVTINPT ASCLVMTTEI LRSMLYRGSE VMREVAWVIF DEIHYMRDSE RGVVWEETII LLPDNVHYVF LSATIPNARQ FAEWICHLHK QPCHVI (3-307 aa encoded by B C028604)

Target Information

SKIV2L2 may be involved in pre-mRNA splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Nucleolar URB1 ensures 3' ETS rRNA removal to prevent exosome surveillance.

Nature

Shan L,Xu G,Yao RW,Luan PF,Huang Y,Zhang PH,Pan YH,Zhang L,Gao X,Li Y,Cao SM,Gao SX,Yang ZH,Li S,Yang LZ,Wang Y,Wong CCL,Yu L,Li J,Yang L,Chen LL

Wed Mar 01 00:00:00 UTC 2023

Nucleolar URB1 ensures 3' ETS rRNA removal to prevent exosome surveillance.

Nature

Shan L,Xu G,Yao RW,Luan PF,Huang Y,Zhang PH,Pan YH,Zhang L,Gao X,Li Y,Cao SM,Gao SX,Yang ZH,Li S,Yang LZ,Wang Y,Wong CCL,Yu L,Li J,Yang L,Chen LL

Wed Mar 01 00:00:00 UTC 2023

TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV.

Nature communications

Matkovic R,Morel M,Lanciano S,Larrous P,Martin B,Bejjani F,Vauthier V,Hansen MMK,Emiliani S,Cristofari G,Gallois-Montbrun S,Margottin-Goguet F

Mon Jan 10 00:00:00 UTC 2022

Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.

RNA (New York, N.Y.)

Jiao AL,Perales R,Umbreit NT,Haswell JR,Piper ME,Adams BD,Pellman D,Kennedy S,Slack FJ

Fri Mar 01 00:00:00 UTC 2019

Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.

RNA (New York, N.Y.)

Jiao AL,Perales R,Umbreit NT,Haswell JR,Piper ME,Adams BD,Pellman D,Kennedy S,Slack FJ

Fri Mar 01 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: ATP-dependent helicase SKIV2L2; ATP-dependent RNA helicase DOB1; ATP-dependent RNA helicase SKIV2L2; Exosome RNA helicase MTR4; functional spliceosome-associated protein 118; Superkiller viralicidic activity 2-like 2; TRAMP-like complex helicase

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Gene Aliases: 2610528A15Rik; DOB1; fSAP118; KIAA0052; mKIAA0052; MTR4; MTREX; RGD1305984; SKIV2L2

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UniProt ID: (Human) P42285, (Mouse) Q9CZU3

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Entrez Gene ID: (Human) 23517, (Mouse) 72198, (Rat) 365668

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Function(s)

RNA helicase activity protein binding ATP binding poly(A) RNA binding nucleotide binding nucleic acid binding helicase activity hydrolase activity hydrolase activity, acting on acid anhydrides hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Process(es)

mRNA splicing, via spliceosome maturation of 5.8S rRNA rRNA processing RNA catabolic process mRNA processing RNA splicing

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SKIV2L2 Polyclonal Antibody

SKIV2L2 Antibody (12719-2-AP) in WB

Product Details

12719-2-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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