Bioss

SLC11A2 Polyclonal Antibody

View all (16) SLC11A2 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

BS-3577R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300
-

Immunohistochemistry (Paraffin) (IHC (P))

1:400
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

Flow Cytometry (Flow)

1:20-1:100
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Chicken, Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human SLC11A2, amino acids 251-350.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: Dct-1; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; microcytic anemia, viable anaemia; Natural resistance-associated macrophage protein 2; NRAMP 2; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2; Solute carrier family 11 member 2; Solute carrier family 11 member 2 (natural resistance-associated macrophage protein 2)

View more View less

Gene Aliases: AHMIO1; DCT1; DMT1; mk; NRAMP2; OK/SW-cl.20; SLC11A2; van

View more View less

UniProt ID: (Human) P49281, (Mouse) P49282, (Rat) O54902

View more View less

Entrez Gene ID: (Human) 4891, (Chicken) 751817, (Mouse) 18174, (Rat) 25715

View more View less

Function(s)
copper ion transmembrane transporter activity iron ion transmembrane transporter activity manganese ion transmembrane transporter activity protein binding hydrogen ion transmembrane transporter activity cadmium ion transmembrane transporter activity cobalt ion transmembrane transporter activity ferrous iron transmembrane transporter activity lead ion transmembrane transporter activity solute:proton symporter activity ferrous iron uptake transmembrane transporter activity transferrin transmembrane transporter activity cadmium ion binding transition metal ion transmembrane transporter activity transporter activity iron ion binding copper ion binding zinc ion binding nickel cation transmembrane transporter activity vanadium ion transmembrane transporter activity nickel cation binding inorganic cation transmembrane transporter activity manganese ion binding cobalt ion binding zinc ion transmembrane transporter activity calcium ion transmembrane transporter activity chromium ion transmembrane transporter activity
Process(es)
transition metal ion transport porphyrin-containing compound metabolic process porphyrin-containing compound biosynthetic process heme biosynthetic process transport ion transport cobalt ion transport copper ion transport iron ion transport manganese ion transport cellular copper ion homeostasis activation of cysteine-type endopeptidase activity involved in apoptotic process learning or memory response to manganese ion nickel cation transport vanadium ion transport ferrous iron transport lead ion transport proton transport cellular response to oxidative stress iron ion transmembrane transport copper ion transmembrane transport nickel cation transmembrane transport dendrite morphogenesis erythrocyte development iron ion homeostasis multicellular organismal iron ion homeostasis cadmium ion transmembrane transport ferrous iron import manganese ion transmembrane transport zinc II ion transmembrane transport cation transmembrane transport hydrogen ion transmembrane transport copper ion import into cell ferrous iron transmembrane transport cellular iron ion homeostasis response to iron ion transferrin transport response to hypoxia detection of oxygen response to lead ion response to cadmium ion cellular response to iron ion cellular response to tumor necrosis factor cellular response to hypoxia
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support