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SLC12A7 Polyclonal Antibody
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Product Details
OSS00290W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 940-990 of human SLC12A7 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and mouse.
Specificity of this antibody: SLC12A7.
Target Information
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Electroneutral potassium-chloride cotransporter 4; furosemide-sensitive KCl cotransporter 4; K-Cl cotransporter 4; K-Cl cotransporter KCC4; potassium/chloride transporter KCC4; slc12a7 {ECO:0000312|EMBL:AAH86339.1, ECO:0000312|RGD:1359672}; solute carrier family 12 (potassium/chloride transporter), member 7; solute carrier family 12 (potassium/chloride transporters), member 7; Solute carrier family 12 member 7
Gene Aliases: AA408796; D13Ertd261e; KCC4; SLC12A7
UniProt ID: (Human) Q9Y666, (Rat) Q5RK27, (Mouse) Q9WVL3
Entrez Gene ID: (Human) 10723, (Rat) 308069, (Mouse) 20499
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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