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Product Details
H00006564-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
1F8
Immunogen
SLC15A1 (NP_005064, 473 a.a. approximately 572 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: VKDGLNQKPE KGENGIRFVN TFNELITITM SGKVYANISS YNASTYQFFP SGIKGFTISS TEIPPQCQPN FNTFYLEFGS AYTYIVQRKN DSCPEVKVFE
Target Information
In mammalian small intestine, the proton-coupled peptide transporter (PEPT) is responsible for the absorption of small peptides arising from digestion of dietary proteins. PEPT1, a hydrogen ion/peptide cotransporter, transports dipeptides and tripeptides, but not free amino acids or peptides with more than three amino acid residues. Its driving force for uphill transport requires proton binding and the presence of an inside-negative membrane potential. PEPT1 is 708 amino acid protein that contains 12 putative membrane-spanning domains. PEPT1 is expressed in Caco-2 cells. PEPT1 seems to play important roles in nutritional and pharmacological therapies. The mammalian kidney expresses a proton-coupled peptide transporter, PEPT2, that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Caco-2 oligopeptide transporter; Intestinal H(+)/peptide cotransporter; intestinal H+/peptide cotransporter; macrophage oligopeptide transporter PEPT1; Oligopeptide transporter, small intestine isoform; Peptide transporter 1; solute carrier family 15 (oligopeptide transporter), member 1; Solute carrier family 15 member 1
Gene Aliases: HPECT1; HPEPT1; PEPT1; SLC15A1
UniProt ID: (Human) P46059
Entrez Gene ID: (Human) 6564
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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