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Invitrogen
SLC16A13 Polyclonal Antibody
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SLC16A13 Antibody (PA5-106681) in IHC (P)
Immunohistochemistry analysis of SLC16A13 in rat brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with SLC16A13 polyclonal antibody (Product # PA5-106681) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-106681
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SLC16A13(Accession Q7RTY0), corresponding to amino acid residues P392-D426.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2854349
Product Specific Information
Antibody detects endogenous levels of total MOT13.
Target Information
Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT13 (Monocarboxylate transporter 13), also known as SLC16A13 (Solute carrier family 16 member 13), is a 426 amino acid multi-pass membrane protein that belongs to the MCT transport family. Functioning as a proton-linked monocarboxylate transporter, MCT13 catalyzes the rapid transports of molecules, such as lactate, across the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MCT 13; monocarboxylate transporter; Monocarboxylate transporter 13; monocarboxylic acid transporter 13; MOT13; solute carrier family 16 (monocarboxylic acid transporters), member 13; Solute carrier family 16 member 13; solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
Gene Aliases: 1700007D07Rik; MCT13; SLC16A13
UniProt ID: (Human) Q7RTY0, (Mouse) Q8CE94, (Rat) Q66HE2
Entrez Gene ID: (Human) 201232, (Mouse) 69309, (Rat) 287451
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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