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Peptide sequence: LFTPIAADLG VGPLIVLRAL EGLGEGVTFP AMHAMWSSWA PPLERSKLLS
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 93%
This gene encodes a membrane transporter that exports free sialic acids that have been cleaved off of cell surface lipids and proteins from lysosomes. Mutations in this gene cause sialic acid storage diseases, including infantile sialic acid storage disorder and and Salla disease, an adult form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AST; FLJ22227; FLJ23268; H(+)/nitrate cotransporter; H(+)/sialic acid cotransporter; hp59; Membrane glycoprotein HP59; sialic acid storage disease; Sialin; sodium/sialic acid cotransporter; solute carrier family 17 (acidic sugar transporter), member 5; solute carrier family 17 (anion/sugar transporter), member 5; Solute carrier family 17 member 5; VEAT; Vesicular excitatory amino acid transporter; vesicular H(+)/Aspartate-glutamate cotransporter
Gene Aliases: AST; ISSD; NSD; SD; SIALIN; SIASD; SLC17A5; SLD
UniProt ID: (Human) Q9NRA2
Entrez Gene ID: (Human) 26503
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