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Invitrogen
SLC19A1 Polyclonal Antibody
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SLC19A1 Antibody (PA1-9553) in WB
PloS one 2013 -
Figure 5 Ectopic overexpression of RFC in FRalpha-positive SKOV-3 counteracted folate-mediated cell proliferation, migration and invasion, and down-regulation of E-cadherin. (A) Cell proliferation rate of SKOV-3 cells with ectopically expressed RFC or control vector (control) treated with 60 nM folate after 5 days displayed as fold change compared to control without folate treatment (0 nM); n = 3; *, P ... View More
Product Details
PA1-9553
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Chicken
/ IgY
Class
Polyclonal
Type
Antibody
Immunogen
Purified recombinant SLC19A1 corresponding to the chromosome 21 gene (Human).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
IgY fraction
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2301780
Product Specific Information
PA1-9553 detects SLC19A1 in human samples.
PA1-9553 has been successfully used in Western blot procedures. By Western blot, PA1-9553 detects a 65 kDa protein representing SLC19A1.
PA1-9553 immunogen is a purified recombinant SLC19A1 corresponding to the chromosome 21 gene (Human).
Target Information
Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cyclic dinucleotide:anion antiporter SLC19A1; Folate:anion antiporter SLC19A1; FOLT; hSLC19A1; IFC-1; Intestinal folate carrier 1; Placental folate transporter; Reduced folate carrier protein; Reduced folate transporter; Reduced folate transporter 1; RFC; RFT-1; solute carrier family 19 (folate transporter), member 1; Solute carrier family 19 member 1
Gene Aliases: CHMD; FLOT1; FOLT; IFC1; REFC; RFC1; SLC19A1
UniProt ID: (Human) P41440
Entrez Gene ID: (Human) 6573
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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