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SLC19A1 Antibody (PA5-80009) in WB
Western blot analysis of SLC19A1 in, Lane 1: rat brain tissue lysates, Lane 2: rat ovary tissue lysates, Lane 3: mouse brain tissue lysates, Lane 4: mouse testicular tissue lysates, Lane 5: mouse ovary tissue lysates, Lane 6: mouse NIH/3T3 whole cell lysates, Lane 7: human placenta tissue lysates, Lane 8: human HEK293 whole cell lysates, Lane 9: monkey COS-7 whole cell lysates, Lane 10: human PC-3 whole cell lysates, Lane 11: human 22RV1 whole cell lysates, Lane 12: human K562 whole cell lysates. Electrophoresis was performed on a 5-20% SD... View More
Product Details
PA5-80009
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human SLC19A1 (202-231aa FLKRPKRSLFFNRDDRGRCETSASELERMN).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2747124
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat brain tissue, rat ovary tissue, mouse brain tissue, mouse testicular tissue, mouse ovary tissue, mouse NIH/3T3 whole cell, human placenta tissue, human HEK293 whole cell, monkey COS-7 whole cell, human PC-3 whole cell, human 22RV1 whole cell, human K562 whole cell.
Target Information
Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cyclic dinucleotide:anion antiporter SLC19A1; folate transporter 1; Folate:anion antiporter SLC19A1; FOLT; hSLC19A1; IFC-1; Intestinal folate carrier 1; intestinal folate carrier protein; Methotrexate carrier 1; methotrexate carrier 2; methotrexate carrier 5; methotrexate carrier 6; MTX-1; Placental folate transporter; Plasma membrane folate antiporter SLC19A1; Reduced folate carrier 1; Reduced folate carrier protein; Reduced folate transporter; Reduced folate transporter 1; RFC; RFC-1; RFC1; RFT-1; solute carrier family 19 (folate transporter), member 1; solute carrier family 19 (sodium/hydrogen exchanger), member 1; Solute carrier family 19 member 1; solute carrier family 19, member 1
Gene Aliases: AI323572; CHMD; FLOT1; FOLT; IFC1; MTX1; REFC; RFC; RFC-1; RFC1; SLC19A1
UniProt ID: (Human) P41440, (Mouse) P41438, (Rat) Q62866
Entrez Gene ID: (Human) 6573, (Mouse) 20509, (Rat) 29723
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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