Proteintech

SLC19A3 Polyclonal Antibody

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SLC19A3 Antibody (13407-1-AP) in WB

Mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 13407-1-AP (SLC19A3 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours.

SLC19A3 Antibody in Immunoprecipitation (IP)

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Product Details

13407-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 10 publications 10 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SLC19A3 Fusion Protein Ag4053 (188-315 aa encoded by BC032014)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: LFLPMPKKS MFFHAKPSRE IKKSSSVNPV LEETHEGEAP GCEEQKPTSE ILSTSGKLNK GQLNSLKPSN VTVDVFVQWF QDLKECYSSK RLFYWSLWWA FATAGFNQVL NYVQILWDYK APSQDSSIY (188-315 aa encoded by BC032014)

Target Information

SLC19A3 encodes a ubiquitously expressed transmembrane thiamine transporter that lacks folate transport activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Impact of Metformin Treatment on Human Placental Energy Production and Oxidative Stress.

Frontiers in cell and developmental biology

Tarry-Adkins JL,Robinson IG,Reynolds RM,Aye ILMH,Charnock-Jones DS,Jenkins B,Koulmann A,Ozanne SE,Aiken CE

Wed Feb 01 00:00:00 UTC 2023

Human adipose tissue gene expression of solute carrier family 19 member 3 (SLC19A3); relation to obesity and weight-loss.

Obesity science & practice

Pereira MJ,Andersson-Assarsson JC,Jacobson P,Kamble P,Taube M,Sjöholm K,Carlsson LMS,Svensson PA

Tue Feb 01 00:00:00 UTC 2022

Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia.

Nature communications

Sheikh A,Tumala B,Vickers TJ,Martin JC,Rosa BA,Sabui S,Basu S,Simoes RD,Mitreva M,Storer C,Tyksen E,Head RD,Beatty W,Said HM,Fleckenstein JM

Sat Nov 12 00:00:00 UTC 2022

Hypoxia inhibits colonic uptake of the microbiota-generated forms of vitamin B1 via HIF-1α-mediated transcriptional regulation of their transporters.

The Journal of biological chemistry

Sabui S,Ramamoorthy K,Romero JM,Simoes RD,Fleckenstein JM,Said HM

Tue Feb 01 00:00:00 UTC 2022

Chronic Voluntary Alcohol Drinking Causes Anxiety-like Behavior, Thiamine Deficiency, and Brain Damage of Female Crossed High Alcohol Preferring Mice.

Frontiers in pharmacology

Xu H,Li H,Liu D,Wen W,Xu M,Frank JA,Chen J,Zhu H,Grahame NJ,Luo J

Sat Sep 25 00:00:00 UTC 2021

Proinflammatory cytokines inhibit thiamin uptake by human and mouse pancreatic acinar cells: involvement of transcriptional mechanism(s).

American journal of physiology. Gastrointestinal and liver physiology

Anandam KY,Srinivasan P,Yasujima T,Al-Juburi S,Said HM

Fri Jan 01 00:00:00 UTC 2021

CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease.

Science translational medicine

Picó S,Parras A,Santos-Galindo M,Pose-Utrilla J,Castro M,Fraga E,Hernández IH,Elorza A,Anta H,Wang N,Martí-Sánchez L,Belloc E,Garcia-Esparcia P,Garrido JJ,Ferrer I,Macías-García D,Mir P,Artuch R,Pérez B,Hernández F,Navarro P,López-Sendón JL,Iglesias T,Yang XW,Méndez R,Lucas JJ

Wed Sep 29 00:00:00 UTC 2021

Effects of Chronic Voluntary Alcohol Drinking on Thiamine Concentrations, Endoplasmic Reticulum Stress, and Oxidative Stress in the Brain of Crossed High Alcohol Preferring Mice.

Neurotoxicity research

Xu H,Liu D,Chen J,Li H,Xu M,Wen W,Frank JA,Grahame NJ,Zhu H,Luo J

Fri Nov 01 00:00:00 UTC 2019

Novel SLC19A3 Promoter Deletion and Allelic Silencing in Biotin-Thiamine-Responsive Basal Ganglia Encephalopathy.

PloS one

Flønes I,Sztromwasser P,Haugarvoll K,Dölle C,Lykouri M,Schwarzlmüller T,Jonassen I,Miletic H,Johansson S,Knappskog PM,Bindoff LA,Tzoulis C

Mon Jul 25 00:00:00 UTC 2016

Novel SLC19A3 Promoter Deletion and Allelic Silencing in Biotin-Thiamine-Responsive Basal Ganglia Encephalopathy.

PloS one

Flønes I,Sztromwasser P,Haugarvoll K,Dölle C,Lykouri M,Schwarzlmüller T,Jonassen I,Miletic H,Johansson S,Knappskog PM,Bindoff LA,Tzoulis C

Mon Jul 25 00:00:00 UTC 2016

Up-regulation of vitamin B1 homeostasis genes in breast cancer.

The Journal of nutritional biochemistry

Zastre JA,Hanberry BS,Sweet RL,McGinnis AC,Venuti KR,Bartlett MG,Govindarajan R

Sun Sep 01 00:00:00 UTC 2013

Up-regulation of vitamin B1 homeostasis genes in breast cancer.

The Journal of nutritional biochemistry

Zastre JA,Hanberry BS,Sweet RL,McGinnis AC,Venuti KR,Bartlett MG,Govindarajan R

Sun Sep 01 00:00:00 UTC 2013

Up-regulation of vitamin B1 homeostasis genes in breast cancer.

The Journal of nutritional biochemistry

Zastre JA,Hanberry BS,Sweet RL,McGinnis AC,Venuti KR,Bartlett MG,Govindarajan R

Sun Sep 01 00:00:00 UTC 2013

Up-regulation of vitamin B1 homeostasis genes in breast cancer.

The Journal of nutritional biochemistry

Zastre JA,Hanberry BS,Sweet RL,McGinnis AC,Venuti KR,Bartlett MG,Govindarajan R

Sun Sep 01 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: solute carrier family 19 (sodium/hydrogen exchanger), member 3; solute carrier family 19 (thiamine transporter), member 3; Solute carrier family 19 member 3; solute carrier family 19, member 3; Thiamine transporter 2; ThTr-2

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Gene Aliases: A230084E24Rik; AI788884; BBGD; SLC19A3; THMD2; THTR2

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UniProt ID: (Human) Q9BZV2, (Mouse) Q99PL8

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Entrez Gene ID: (Human) 80704, (Rat) 316559, (Mouse) 80721

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Function(s)

thiamine transmembrane transporter activity thiamine uptake transmembrane transporter activity folic acid transporter activity

Process(es)

thiamine-containing compound metabolic process thiamine transmembrane transport drug transmembrane transport transport folic acid transport thiamine transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SLC19A3 Polyclonal Antibody

SLC19A3 Antibody (13407-1-AP) in WB

Product Details

13407-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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