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Immunogen sequence: NLVEATFKQY RTKTTPVVKS PKVAPEEAPP RRILIYGVQE ENGSHVQNFA LDLTPPPEVV YKSEPGTSDG M
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 89%.
This gene belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family, SLC1A7 subfamily. As transportor of L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.It interacts with the PDZ domains of DLG4. Expressed primarily in retina. Detectable in liver, heart, muscle and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Excitatory amino acid transporter 5; excitatory amino acid transporter 5 (retinal glutamate transporter); Retinal glutamate transporter; solute carrier family 1 (glutamate transporter), member 7; Solute carrier family 1 member 7
Gene Aliases: AAAT; EAAT5; SLC1A7
UniProt ID: (Human) O00341
Entrez Gene ID: (Human) 6512
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