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Positive Samples: Mouse eye; Cellular Location: Membrane, Multi-pass membrane protein
Immunogen sequence: DFARDTGTEK LLPCETKPVS LQEIVAAQQN GCVKSVAEAS ELTLGPTCPH HVPVQVEQDE ELPAASLNHC TIQISELETN V
This gene belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family, SLC1A7 subfamily. As transportor of L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.It interacts with the PDZ domains of DLG4. Expressed primarily in retina. Detectable in liver, heart, muscle and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Excitatory amino acid transporter 5; excitatory amino acid transporter 5 (retinal glutamate transporter); Retinal glutamate transporter; solute carrier family 1 (glutamate transporter), member 7; Solute carrier family 1 member 7
Gene Aliases: A930031E15Rik; AAAT; EAAT5; SLC1A7
UniProt ID: (Human) O00341, (Mouse) Q8JZR4
Entrez Gene ID: (Human) 6512, (Mouse) 242607
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