Proteintech

SLC20A1 Polyclonal Antibody

SLC20A1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SLC20A1 Antibody (12423-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human liver tissue slide using (Product # 12423-1-AP) (SLC20A1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

SLC20A1 Antibody in Immunoprecipitation (IP)

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Product Details

12423-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Flow Cytometry (Flow)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SLC20A1 Fusion Protein Ag3084 (249-570 aa encoded by BC019944)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.61 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: FVCPRMKRK IEREIKCSPS ESPLMEKKNS LKEDHEETKL SVGDIENKHP VSEVGPATVP LQAVVEERTV SFKLGDLEEA PERERLPSVD LKEETSIDST VNGAVQLPNG NLVQFSQAVS NQINSSGHYQ YHTVHKDSGL YKELLHKLHL AKVGDCMGDS GDKPLRRNNS YTSYTMAICG MPLDSFRAKE GEQKGEEMEK LTWPNADSKK RIRMDSYTSY CNAVSDLHSA SEIDMSVKAE MGLGDRKGSN GSLEEWYDQD KPEVSLLFQF LQILTACFGS FAHGGNDVSN AIGPLVALYL VYDTGDVSSK VATPIWLLLY GGV (249-570 aa encoded by BC019944)

Target Information

Retrovirus receptors allow infection of human and murine cells by various retroviruses. The receptors that have been identified at the molecular level include CD4 for human immunodeficiency virus, Rec1 for murine ecotropic virus, and GLVR1 for gibbon ape leukemia virus. These 3 proteins show no homology to one another at the DNA or protein level. GLVR1 is a sodium-dependent phosphate symporter.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Modulating Temporospatial Phosphate Equilibrium by Nanoparticulate Mineralized Collagen Materials Induces Osteogenesis via PiT-1 and PiT-2.

Advanced healthcare materials

Ren X,Zhou Q,Bedar M,Foulad D,Huang KX,Dejam D,Dahan NJ,Kolliopoulos V,Harley BAC,Lee JC

Sat Jul 01 00:00:00 UTC 2023

GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity.

Nature cancer

Watson DC,Bayik D,Storevik S,Moreino SS,Sprowls SA,Han J,Augustsson MT,Lauko A,Sravya P,Røsland GV,Troike K,Tronstad KJ,Wang S,Sarnow K,Kay K,Lunavat TR,Silver DJ,Dayal S,Joseph JV,Mulkearns-Hubert E,Ystaas LAR,Deshpande G,Guyon J,Zhou Y,Magaut CR,Seder J,Neises L,Williford SE,Meiser J,Scott AJ,Sajjakulnukit P,Mears JA,Bjerkvig R,Chakraborty A,Daubon T,Cheng F,Lyssiotis CA,Wahl DR,Hjelmeland AB,Hossain JA,Miletic H,Lathia JD

Mon May 01 00:00:00 UTC 2023

Both high glucose and phosphate overload promote senescence-associated calcification of vascular muscle cells.

International urology and nephrology

Zhang M,Li T,Tu Z,Zhang Y,Wang X,Zang D,Xu D,Feng Y,He F,Ni M,Wang D,Zhou H

Sat Oct 01 00:00:00 UTC 2022

Iron Sucrose: A Double-Edged Sword in High Phosphate Media-Induced Vascular Calcification.

Calcified tissue international

Wang P,Guo C,Pan H,Chen W,Peng D

Tue Jun 01 00:00:00 UTC 2021

SLC20A1 Is Involved in Urinary Tract and Urorectal Development.

Frontiers in cell and developmental biology

Rieke JM,Zhang R,Braun D,Yilmaz Ö,Japp AS,Lopes FM,Pleschka M,Hilger AC,Schneider S,Newman WG,Beaman GM,Nordenskjöld A,Ebert AK,Promm M,Rösch WH,Stein R,Hirsch K,Schäfer FM,Schmiedeke E,Boemers TM,Lacher M,Kluth D,Gosemann JH,Anderberg M,Barker G,Holmdahl G,Läckgren G,Keene D,Cervellione RM,Giorgio E,Di Grazia M,Feitz WFJ,Marcelis CLM,Van Rooij IALM,Bökenkamp A,Beckers GMA,Keegan CE,Sharma A,Dakal TC,Wittler L,Grote P,Zwink N,Jenetzky E,Brusco A,Thiele H,Ludwig M,Schweizer U,Woolf AS,Odermatt B,Reutter H

Wed Feb 14 00:00:00 UTC 2024

Oxidative stress by Ca²⁺ overload is critical for phosphate-induced vascular calcification.

American journal of physiology. Heart and circulatory physiology

Nguyen NT,Nguyen TT,Da Ly D,Xia JB,Qi XF,Lee IK,Cha SK,Park KS

Tue Dec 01 00:00:00 UTC 2020

Phosphate (P_i)-regulated heterodimerization of the high-affinity sodium-dependent P_i transporters PiT1/Slc20a1 and PiT2/Slc20a2 underlies extracellular P_i sensing independently of P_i uptake.

The Journal of biological chemistry

Bon N,Couasnay G,Bourgine A,Sourice S,Beck-Cormier S,Guicheux J,Beck L

Fri Feb 09 00:00:00 UTC 2018

Intracellular alkalinization by phosphate uptake via type III sodium-phosphate cotransporter participates in high-phosphate-induced mitochondrial oxidative stress and defective insulin secretion.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Nguyen TT,Quan X,Xu S,Das R,Cha SK,Kong ID,Shong M,Wollheim CB,Park KS

Thu Dec 01 00:00:00 UTC 2016

Intracellular alkalinization by phosphate uptake via type III sodium-phosphate cotransporter participates in high-phosphate-induced mitochondrial oxidative stress and defective insulin secretion.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Nguyen TT,Quan X,Xu S,Das R,Cha SK,Kong ID,Shong M,Wollheim CB,Park KS

Thu Dec 01 00:00:00 UTC 2016

Bioinformatics

Protein Aliases: DKFZp686J2397; FLJ41426; Gibbon ape leukemia virus receptor 1; GLVR-1; Leukemia virus receptor 1 homolog; Phosphate transporter 1; PiT-1; Sodium-dependent phosphate transporter 1; solute carrier family 20 (phosphate transporter), member 1; Solute carrier family 20 member 1

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Gene Aliases: Glvr-1; GLVR1; PiT-1; PIT1; SLC20A1

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UniProt ID: (Human) Q8WUM9

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Entrez Gene ID: (Human) 6574

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Function(s)

signal transducer activity receptor activity inorganic phosphate transmembrane transporter activity high-affinity inorganic phosphate:sodium symporter activity sodium:phosphate symporter activity sodium:inorganic phosphate symporter activity sodium-dependent phosphate transmembrane transporter activity

Process(es)

phosphate-containing compound metabolic process transport ion transport signal transduction phosphate ion transmembrane transport sodium ion transmembrane transport positive regulation of I-kappaB kinase/NF-kappaB signaling sodium-dependent phosphate transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SLC20A1 Polyclonal Antibody

SLC20A1 Antibody (12423-1-AP) in IHC (P)

Product Details

12423-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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