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Alomone Labs, LTD
SLC22A1 Polyclonal Antibody
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FIGURE: 1 / 1
SLC22A1 Antibody (ACT-011-200UL) in WB
Western blot analysis of rat small intestine lysate (lanes 1 and 3) and rat H4-II-E-C3 hepatoma cell lysate (lanes 2 and 4): - 1-2. Anti-SLC22A1 Antibody (#ACT-011), (1:200).3-4. Anti-SLC22A1 Antibody , preincubated with SLC22A1 Blocking Peptide (#BLP-CT011).
Product Details
ACT-011-200UL
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)ENLGRRKSKAKENT, corresponding to amino acid residues 530- 543 of rat OCT1, Intracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1-Oct; DKFZp313N1010; FLJ25043; FLJ37489; H oct1_cds; mOCT1; Organic cation transporter 1; rOCT1; Solute carrier family 22 member 1; solute carrier family 22, member 1; SYK
Gene Aliases: Lx1; Oct1; Orct; Orct1; Roct1; Slc22a1
UniProt ID: (Rat) Q63089, (Mouse) O08966
Entrez Gene ID: (Rat) 24904, (Mouse) 20517
acetylcholine transmembrane transporter activity
dopamine transmembrane transporter activity
norepinephrine transmembrane transporter activity
monoamine transmembrane transporter activity
secondary active organic cation transmembrane transporter activity
organic cation transmembrane transporter activity
quaternary ammonium group transmembrane transporter activity
identical protein binding
protein homodimerization activity
transporter activity
ion transmembrane transporter activity
transmembrane transporter activity
cation transport
neurotransmitter transport
drug transmembrane transport
establishment or maintenance of transmembrane electrochemical gradient
organic cation transport
quaternary ammonium group transport
monoamine transport
dopamine transport
norepinephrine transport
epinephrine transport
protein homooligomerization
ammonium transmembrane transport
cation transmembrane transport
acetate ester transport
transport
ion transport
ion transmembrane transport
transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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