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Proteintech
SLC25A10 Polyclonal Antibody
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Product Details
12086-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLC25A10 Fusion Protein Ag2719 (1-296 aa encoded by BC015797)
Conjugate
Form
Liquid
Concentration
0.41 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAAEARVSR WYFGGLASCG AACCTHPLDL LKVHLQTQQE VKLRMTGMAL RVVRTDGILA LYSGLSASLC RQMTYSLTRF AIYETVRDRV AKGSQGPLPF HEKVLLGSVS GLAGGFVGTP ADLVNVRMQN DVKLPQGQRR NYAHALDGLY RVAREEGLRR LFSGATMASS RGALVTVGQL SCYDQAKQLV LSTGYLSDNI FTHFVASFIA AAGDEPPPQG GCATFLCQPL DVLKTRLMNS KGEYQGVFHC AVETAKLGPL AFYKGLVPAG IRLIPHTVLT FVFLEQLRKN FGIKVPS (1-296 aa encoded by BC015797)
Target Information
The mitochondrial dicarboxylate carrier protein (mDIC) belongs to superfamily of mitochondrial transporters. It has been demonstrated that the expression of mDIC leads to hyperpolarization of the mitochondria, as well as succinate uptake by the mitochondria. It is highly expressed in adipose tissue, where its expression is downregulated by insulin and upregulated by free fatty acids. mDIC is also thought to play a role in glyceroneogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DIC; dicarboxylate ion carrier; dicarboxylate transporter), member 10; Mitochondrial dicarboxylate carrier; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 10; solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10; Solute carrier family 25 member 10
Gene Aliases: DIC; SLC25A10
UniProt ID: (Human) Q9UBX3, (Mouse) Q9QZD8, (Rat) O89035
Entrez Gene ID: (Human) 1468, (Mouse) 27376, (Rat) 170943
structural constituent of ribosome
dicarboxylic acid transmembrane transporter activity
protein binding
phosphate ion transmembrane transporter activity
sulfate transmembrane transporter activity
thiosulfate transmembrane transporter activity
malate transmembrane transporter activity
succinate transmembrane transporter activity
secondary active transmembrane transporter activity
antiporter activity
transport
phosphate ion transport
mitochondrial transport
sulfate transport
thiosulfate transport
malate transport
succinate transport
phosphate ion transmembrane transport
transmembrane transport
succinate transmembrane transport
malate transmembrane transport
sulfate transmembrane transport
gluconeogenesis
translation
ion transport
dicarboxylic acid transport
sulfide oxidation, using sulfide:quinone oxidoreductase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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