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SLC25A5/SLC25A6 Polyclonal Antibody
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Product Details
OSS00325W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 30-100 of human SLC25A6 conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: SLC25A6, 5.
Target Information
SLC25A5 and SLC25A6 are members of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this genes functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. SLC25A5 forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of SLC25A5 gene has been shown to induce apoptosis and inhibit tumor growth. SLC25A6 is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenine nucleotide translocator 2; adenine nucleotide translocator 2 (fibroblast); Adenine nucleotide translocator 3; ADP,ATP carrier protein 2; ADP,ATP carrier protein 3; ADP,ATP carrier protein, fibroblast isoform; ADP,ATP carrier protein, isoform T2; ADP,ATP carrier protein, liver; ADP/ATP translocase 2; ADP/ATP translocase 3; ADP/ATP translocator of liver; ANT 2; ANT 3; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6; Solute carrier family 25 member 5; Solute carrier family 25 member 6
Gene Aliases: 2F1; AAC2; AAC3; ANT; ANT 2; ANT 3; ANT2; ANT3; ANT3Y; CDABP0051; SLC25A5; SLC25A6; T2; T3
UniProt ID: (Human) P05141, (Human) P12236
Entrez Gene ID: (Human) 292, (Human) 293
translation
protein targeting to mitochondrion
apoptotic process
adenine transport
ADP transport
ATP transport
active induction of host immune response by virus
regulation of insulin secretion
transmembrane transport
transport
chromosome segregation
positive regulation of cell proliferation
viral process
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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