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Invitrogen
SLC34A1 Polyclonal Antibody
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SLC34A1 Antibody (PA5-120232) in WB
Western blot analysis of SLC34A1 in various lysates. Samples were incubated with SLC34A1 Polyclonal antibody (Product # PA5-120232) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-120232
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 562-639 of human SLC34A1 (NP_0030433)
Conjugate
Form
Liquid
Concentration
0.52 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2913804
Product Specific Information
Positive test controls include: 293T, A-549, U-87MG, Mouse kidney, Rat lung. The target is usually found in the following locations: Membrane, Multi-pass membrane protein.
Immunogen sequence: QSRSPGHLPK WLQTWDFLPR WMHSLKPLDH LITRATLCCA RPEPRSPPLP PRVFLEELPP ATPSPRLALP AHHNATRL
Target Information
Renal tubular reabsorption of phosphate is critical to the maintenance of phosphate homeostasis in mammals. The brush-border membrane Na+/Pi cotransport systems in proximal tubules play a major role in this process. The renal Na(+)/P(i) cotransporter NPT2 is expressed in the brush border membrane (BBM) of proximal tubular cells. NPT2 gene expression is crucial for PTH effects on renal P(i) handling. However, renal expression of the sodium/phosphate cotransporter gene, NPT2, is not required for regulation of renal 1 alpha-hydroxylase by phosphate. NPT2 is an integral membrane protein expressed in kidney and lung. The gene encoding human NPT1 maps to chromosome 6q21.3-p23, while the gene encoding human NPT2 maps to chromosome 5q35.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Na(+)-dependent phosphate cotransporter 2A; Na(+)/Pi cotransporter 2A; Na+-phosphate cotransporter type II; Na/Pi cotransporter; naPi-2a; NaPi-3; naPi-7; renal Na+/Pi transporter; renal sodium-dependent phosphate transporter; Sodium-dependent phosphate transport protein 2A; Sodium-phosphate transport protein 2A; sodium/phosphate co-transporter; Sodium/phosphate cotransporter 2A; solute carrier family 17 (sodium phosphate), member 2; solute carrier family 17 (sodium/hydrogen exchanger) member 2; solute carrier family 17 (sodium/hydrogen exchanger), member 2; solute carrier family 34 (sodium phosphate), member 1; solute carrier family 34 (type II sodium/phosphate cotransporter), member 1; Solute carrier family 34 member 1; solute carrier family 34, member 1; type IIa Na+/Pi-cotransporter
Gene Aliases: FRTS2; HCINF2; NaPi-2; NAPI-3; NaPi-IIa; NaPi2A; NPHLOP1; NPT2; Npt2a; NPTIIa; SLC11; SLC17A2; SLC34A1
UniProt ID: (Human) Q06495, (Rat) Q06496
Entrez Gene ID: (Human) 6569, (Mouse) 20505, (Rat) 25548
transport
ion transport
sodium ion transport
phosphate ion transport
response to lead ion
phosphate ion transmembrane transport
sodium-dependent phosphate transport
positive regulation of membrane potential
response to cadmium ion
response to mercury ion
bone remodeling
protein homooligomerization
phosphate ion homeostasis
arsenate ion transmembrane transport
positive regulation of sodium-dependent phosphate transport
positive regulation of phosphate transmembrane transport
ossification
kidney development
response to nutrient
glycoprotein metabolic process
response to magnesium ion
response to estradiol
response to vitamin A
response to potassium ion
indole metabolic process
response to drug
response to peptide hormone
response to growth hormone
response to parathyroid hormone
cellular response to metal ion
cellular response to parathyroid hormone stimulus
tricarboxylic acid metabolic process
cellular response to staurosporine
response to thyroid hormone
dentinogenesis
gentamycin metabolic process
response to peptide
cellular phosphate ion homeostasis
sodium ion transmembrane transport
cellular protein metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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