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FIGURE: 1 / 2
Positive Samples: Mouse brain, Mouse kidney, Rat brain; Cellular Location: Membrane, Multi-pass membrane protein
Immunogen sequence: MAAAAAAGSG TPREEEGPAG EAAASQPQAP TSVPGARLSR LPLARVKALV KADPDVTLAG QEAIFILARA AELFVETIAK DAYCCAQQGK RKTLQRRDLD NAIEAVDEFA FLEGTLD
This gene encodes a member of SLC34A transporter family of proteins, and is expressed primarily in the kidney. It is involved in transporting phosphate into cells via sodium cotransport in the renal brush border membrane, and contributes to the maintenance of inorganic phosphate concentration in the kidney. Mutations in this gene are associated with hereditary hypophosphatemic rickets with hypercalciuria. Alternatively spliced transcript variants varying in the 5' UTR have been found for this gene.
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Protein Aliases: Na(+)-dependent phosphate cotransporter 2C; Na(+)/Pi cotransporter 2C; Na+/Pi-cotransporter type IIc; naPi-2c; Sodium-dependent phosphate transport protein 2C; sodium-phosphate cotransporter IIC; Sodium-phosphate transport protein 2C; Sodium/inorganic phosphate cotransporter IIC; Sodium/phosphate cotransporter 2C; solute carrier family 34 (sodium phosphate), member 3; solute carrier family 34 (type II sodium/phosphate contransporter), member 3; solute carrier family 34 (type II sodium/phosphate cotransporter), member 3; Solute carrier family 34 member 3; type IIc Na+/Pi cotransporter; type IIc Na+/Pi-cotransporter; type IIc NaPi-cotransporter-v1
Gene Aliases: AI649385; HHRH; naPi-2c; NPT2C; Npt2c-v1; NPTIIC; SLC34A3
UniProt ID: (Human) Q8N130, (Rat) Q8K4R8, (Mouse) Q80SU6
Entrez Gene ID: (Human) 142680, (Rat) 246234, (Mouse) 142681
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