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Abnova
SLC39A10 Monoclonal Antibody (1F6)
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Product Details
H00057181-M03
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1F6
Immunogen
SLC39A10 (NP_065075, 514 a.a. approximately 621 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: CIRMFKHYKQ QRGKQKWFMK QNTEESTIGR KLSDHKLNNT PDSDWLQLKP LAGTDDSVVS EDRLNETELT DLEGQQESPP KNYLCIEEEK IIDHSHSDGL HTIHEHDL
Target Information
ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating that ZIP10 is positively regulated by thyroid hormones. ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and possibly a target for novel treatment strategies. At least three isoforms of ZIP10 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: solute carrier family 39 (metal ion transporter), member 10; solute carrier family 39 (zinc transporter), member 10; Solute carrier family 39 member 10; Zinc transporter ZIP10; ZIP-10; Zrt- and Irt-like protein 10
Gene Aliases: KIAA1265; LZT-Hs2; SLC39A10; ZIP10
UniProt ID: (Human) Q9ULF5
Entrez Gene ID: (Human) 57181
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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