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Abnova
SLC39A5 Polyclonal Antibody, MaxPab™
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Product Details
H00283375-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLC39A5 (NP_775867, 1 a.a. approximately 539 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGSPVSHLLA GFCVWVVLGW VGGSVPNLGP AEQEQNHYLA QLFGLYGENG TLTAGGLARL LHSLGLGRVQ GLRLGQHGPL TGRAASPAAD NSTHRPQNPE LSVDVWAGMP LGPSGWGDLE ESKAPHLPRG PAPSGLDLLH RLLLLDHSLA DHLNEDCLNG SQLLVNFGLS PAAPLTPRQF ALLCPALLYQ IDSRVCIGAP APAPPGDLLS ALLQSALAVL LLSLPSPLSL LLLRLLGPRL LRPLLGFLGA LAVGTLCGDA LLHLLPHAQE GRHAGPGGLP EKDLGPGLSV LGGLFLLFVL ENMLGLLRHR GLRPRCCRRK RRNLETRNLD PENGSGMALQ PLQAAPEPGA QGQREKNSQH PPALAPPGHQ GHSHGHQGGT DITWMVLLGD GLHNLTDGLA IGAAFSDGFS SGLSTTLAVF CHELPHELGD FAMLLQSGLS FRRLLLLSLV SGALGLGGAV LGVGLSLGPV PLTPWVFGVT AGVFLYVALV DMLPALLRPP EPLPTPHVLL QGLGLLLGGG LMLAITLLEE RLLPVTTEG
Target Information
The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC34778; solute carrier family 39 (metal ion transporter), member 5; solute carrier family 39 (zinc transporter), member 5; Solute carrier family 39 member 5; Zinc transporter ZIP5; ZIP-5; Zrt- and Irt-like protein 5
Gene Aliases: LZT-Hs7; MYP24; SLC39A5; ZIP5
UniProt ID: (Human) Q6ZMH5
Entrez Gene ID: (Human) 283375
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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