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Proteintech
SLC4A8 Polyclonal Antibody
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Product Details
12531-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLC4A8 Fusion Protein Ag3227 (1-352 aa encoded by BC025994)
Conjugate
Form
Liquid
Concentration
0.18 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPAAGSNEP DGVLSYQRPD EEAVVDQGGT STILNIHYEK EELEGHRTLY VGVRMPLGRQ SHRHHRTHGQ KHRRRGRGKG ASQGEEGLEA LAHDTPSQRV QFILGTEEDE EHVPHELFTE LDEICMKEGE DAEWKETARW LKFEEDVEDG GERWSKPYVA TLSLHSLFEL RSCLINGTVL LDMHANSIEE ISDLILDQQE LSSDLNDSMR VKVREALLKK HHHQNEKKRN NLIPIVRSFA EVGKKQSDPH LMDKHGQTVS PQSVPTTNLE VKNGVNCEHS PVDLSKVDLH FMKKIPTGAE ASNVLVGEVD ILDRPIVAFV RLSPAVLLSG LTEVPIPTRF LFILLGPVGK GQQ (1-352 aa encoded by BC025994)
Target Information
Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Electroneutral Na(+)-driven Cl-HCO3 exchanger; Electroneutral Na+-driven Cl-HCO3 exchanger; Electroneutral sodium bicarbonate exchanger 1; k-NBC3; Na-driven Cl-HCO3 exchanger NDCBE1-A; Na-driven Cl-HCO3 exchanger NDCBE1-B; Na-driven Cl-HCO3 exchanger NDCBE1-C; slc4a8; slc4a8 {ECO:0000312|RGD:735164}; sodium bicarbonate cotransporter isoform 3 kNBC-3; solute carrier family 4 (anion exchanger), member 8; Solute carrier family 4 member 8; solute carrier family 4, sodium bicarbonate cotransporter, member 8
Gene Aliases: AW493845; C230026C11; KIAA0739; kNBC-3; NBC; NBC3; NDCBE; NDCBE1; SLC4A8
UniProt ID: (Human) Q2Y0W8, (Mouse) Q8JZR6, (Rat) Q6RVG2
Entrez Gene ID: (Human) 9498, (Mouse) 59033, (Rat) 315311
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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