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Invitrogen
SLC5A12 Polyclonal Antibody
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SLC5A12 Antibody (PA5-110389) in WB
Western blot analysis of SLC5A12 in extracts of various cell lines. Samples were incubated with SLC5A12 Polyclonal antibody (Product # PA5-110389) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-110389
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 200-280 of human SLC5A12 (NP_848593.2).
Conjugate
Form
Liquid
Concentration
1.02 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2855800
Product Specific Information
Immunogen sequence: LIQGSTHAGG FHNVLEQSTN GSRLHIFDFD VDPLRRHTFW TITVGGTFTW LGIYGVNQST IQRCISCKTE KHAKLALYFN L
Target Information
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Electroneutral sodium monocarboxylate cotransporter; Low-affinity sodium-lactate cotransporter; Sodium-coupled monocarboxylate transporter 2; sodium-iodide related cotransporter; solute carrier family 5 (sodium/glucose cotransporter), member 12; solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12; Solute carrier family 5 member 12
Gene Aliases: SLC5A12; SMCT2
UniProt ID: (Human) Q1EHB4
Entrez Gene ID: (Human) 159963
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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