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Invitrogen
SLC5A12 Polyclonal Antibody
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Product Details
PA5-63910
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SLC5A12. Recombinant protein control fragment (Product #RP-104133).
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2647540
Product Specific Information
Immunogen sequence: QGSTHAGGFH NVLEQSTNGS RLHIFDFDVD PLRRH
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.
Target Information
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Electroneutral sodium monocarboxylate cotransporter; Low-affinity sodium-lactate cotransporter; Sodium-coupled monocarboxylate transporter 2; sodium-iodide related cotransporter; solute carrier family 5 (sodium/glucose cotransporter), member 12; solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12; Solute carrier family 5 member 12
Gene Aliases: SLC5A12; SMCT2
UniProt ID: (Human) Q1EHB4
Entrez Gene ID: (Human) 159963
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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