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Proteintech
SLC6A11 Polyclonal Antibody
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Product Details
13920-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLC6A11 Fusion Protein Ag4927
Conjugate
Form
Liquid
Concentration
650 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
Slc6a11 encode GABA transporters that are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) and mediate the rapid removal of GABA and maintain low extracellular levels. Four 12-TM domain transporters have been identified and localized to neurons and glia. The protein encoded by the Slc6a11 gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in the Slc6a11 gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for the Slc6a11 gene. Diseases associated with SLC6A11 include Tricuspid Valve Stenosis and Pulmonary Valve Insufficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GABA transporter 3; gamma-aminobutyric acid (GABA-A) transporter 4; GAT-3; GAT-4; Sodium- and chloride-dependent GABA transporter 3; Sodium- and chloride-dependent GABA transporter 4; solute carrier family 6 (neurotransmitter transporter), member 11; solute carrier family 6 (neurotransmitter transporter, GABA), member 11; Solute carrier family 6 member 11
Gene Aliases: D930045G19Rik; E130202I16Rik; GABT3; Gabt4; GAT-3; Gat-4; GAT3; GAT4; SLC6A11
UniProt ID: (Human) P48066, (Mouse) P31650
Entrez Gene ID: (Human) 6538, (Mouse) 243616
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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