Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
SLC7A2 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 5
SLC7A2 Antibody (PA5-89910) in IHC (P)
Immunohistochemistry analysis of SLC7A2 in paraffin-embedded human mammary cancer. Samples were incubated with SLC7A2 Polyclonal antibody (Product # PA5-89910) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-89910
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 559-658 of human SLC7A2 (NP_0010085393)
Conjugate
Form
Liquid
Concentration
1.18 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2805837
Product Specific Information
Immunogen sequence: PRNLSSPFIF HEKTSEF
Positive Samples: 293T, HepG2, HeLa, Mouse liver, Mouse brain, Rat liver; Cellular Location: Cell membrane, Multi-pass membrane protein
Target Information
The protein encoded by this gene is a cationic amino acid transporter and a member of the APC (amino acid-polyamine-organocation) family of transporters. The encoded membrane protein is responsible for the cellular uptake of arginine, lysine and ornithine. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 20.5; amino acid transporter, cationic 2 (low affinity); CAT-2; Cationic amino acid transporter 2; cationic amino acid transporter 2A; cationic amino acid transporter 2B; cationic amino acid transporter-2A; Low affinity cationic amino acid transporter 2; solute carrier family 7 (cationic amino acid transporter, y+ system), member 2; Solute carrier family 7 member 2; solute carrier family 7, member 2; T-cell early activation protein; TEA
Gene Aliases: 20.5; AI158848; ATRC2; CAT-2; CAT2; Cat2a; Cat2b; HCAT2; SLC7A2; Tea
UniProt ID: (Human) P52569, (Mouse) P18581, (Rat) B5D5N9
Entrez Gene ID: (Human) 6542, (Mouse) 11988, (Rat) 64554
high-affinity arginine transmembrane transporter activity
high-affinity lysine transmembrane transporter activity
amino acid transmembrane transporter activity
basic amino acid transmembrane transporter activity
L-amino acid transmembrane transporter activity
antiporter activity
low-affinity L-arginine transmembrane transporter activity
high-affinity L-ornithine transmembrane transporter activity
L-ornithine transmembrane transporter activity
arginine transmembrane transporter activity
L-lysine transmembrane transporter activity
L-arginine transmembrane transporter activity
nitric oxide production involved in inflammatory response
cellular amino acid metabolic process
nitric oxide biosynthetic process
transport
amino acid transport
L-amino acid transport
arginine transport
macrophage activation
regulation of macrophage activation
regulation of inflammatory response
L-arginine import across plasma membrane
L-lysine import across plasma membrane
L-ornithine import across plasma membrane
basic amino acid transmembrane transport
amino acid transmembrane transport
transmembrane transport
L-arginine transport
L-ornithine transmembrane transport
L-arginine transmembrane transport
arginine transmembrane transport
cation transmembrane transport
L-alpha-amino acid transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support