Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Peptide sequence: VDTSSSMWIY VFLGNLLRGI GETPIQPLGI AYLDDFASED NAAFYIGCVQ
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%
This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: OAT-RP-5; OATP-14; OATP-F; OATP1C1; Organic anion transporter 1C1; Organic anion transporter F; Organic anion transporter polypeptide-related protein 5; organic anion transporting polypeptide 14; Organic anion-transporting polypeptide 14; solute carrier family 21 (organic anion transporter), member 14; Solute carrier family 21 member 14; Solute carrier organic anion transporter family member 1C1; solute carrier organic anion transporter family, member 1C1; Thyroxine transporter
Gene Aliases: OATP-F; OATP1; OATP14; OATP1C1; OATPF; OATPRP5; SLC21A14; SLCO1C1
UniProt ID: (Human) Q9NYB5
Entrez Gene ID: (Human) 53919
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