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Invitrogen
SLIT1 Polyclonal Antibody
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FIGURE: 1 / 2
SLIT1 Antibody (PA5-119606) in ICC/IF
SLIT1 Polyclonal Antibody detects SLIT1 protein by immunofluorescent analysis. Sample: DIV9 rat E18 primary cortical neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: SLIT1 stained by SLIT1 Polyclonal Antibody (Product # PA5-119606) diluted at 1:500. Red: Tau, stained by Tau antibody [GT287] diluted at 1:500. Blue: Fluoroshield with DAPI .
Product Details
PA5-119606
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of mouse SLIT1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.81 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2913179
Product Specific Information
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target Information
SLIT1 is thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Multiple EGF-like domains protein 4; multiple epidermal growth factor-like domains 4; Multiple epidermal growth factor-like domains protein 4; Slit homolog 1 protein; Slit-1
Gene Aliases: Kiaa0813; MEGF4; mKIAA0813; Slil1; Slit1
UniProt ID: (Rat) O88279, (Mouse) Q80TR4
Entrez Gene ID: (Rat) 65047, (Mouse) 20562
axonogenesis
axon guidance
brain development
motor neuron axon guidance
spinal cord development
olfactory bulb development
chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration
tangential migration from the subventricular zone to the olfactory bulb
telencephalon cell migration
retinal ganglion cell axon guidance
dorsal/ventral axon guidance
establishment of nucleus localization
neuron projection morphogenesis
negative regulation of axon extension involved in axon guidance
axon extension involved in axon guidance
negative chemotaxis
negative regulation of synapse assembly
multicellular organism development
nervous system development
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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