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Proteintech
SLMAP Polyclonal Antibody
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Product Details
25220-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLMAP Fusion Protein Ag18162 (479-828 aa encoded by BC115701)
Conjugate
Form
Liquid
Concentration
0.34 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody recognizes all of these isoforms in mouse heart lysate.
Immunogen sequence: VSLLKDDLQ GAQSEIEAKQ EIQHLRKELI EAQELARTSK QKCFELQALL EEERKAYRNQ VEESTKQIQV LQAQLQRLHI DTENLREEKD SEITSTRDEL LSARDEILLL HQAAAKVASE RDTDIASLQE ELKKVRAELE RWRKAASEYE KEITSLQNSF QLRCQQCEDQ QREEATRLQG ELEKLRKEWN ALETECHSLK RENVLLSSEL QRQEKELHNS QKQSLELTSD LSILQMSRKE LENQVGSLKE QHLRDSADLK TLLSKAENQA KDVQKEYEKT QTVLSELKLK FEMTEQEKQS ITDELKQCKN NLKLLREKGN NKPWPWMPML AALVAVTAIV LYVPGLARAS P (479-828 aa encoded by BC115701)
Target Information
Sarcolemmal membrane associated protein (SLMAP) is a tail-anchored membrane protein involved in the docking and membrane fusion process via protein-protein interactions. Deregulation of SLMAP expression plays an important role in type 2 diabetes, and changes in SLMAP expression are linked to hyperglycemia and diabetes. SLMAPs are components of cardiac membranes and have been identified as a novel regulator of cardiac function. There are several isoforms of SLMAPs with varying molecular size (35, 45, 63, and 83-91 kDa) as a result of alternative splicing. The short 35- kDa isoform is predominantly expressed in cardiac and slow-twitch skeletal muscle, while the 83- to 91- kDa isoform is ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Sarcolemmal membrane-associated protein; Sarcolemmal-associated protein
Gene Aliases: D330001L02Rik; KIAA1601; mKIAA1601; SLAP; SLMAP; UNQ1847/PRO3577
UniProt ID: (Human) Q14BN4, (Mouse) Q3URD3
Entrez Gene ID: (Human) 7871, (Mouse) 83997
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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