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Invitrogen
SLN Monoclonal Antibody (14G1A12)
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SLN Antibody (MA5-50293) in IHC (P)
Immunohistochemistry analysis with a SLN monoclonal antibody (Product # MA5-50293) using a dilution of 1:60 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 min at RT. Then primary antibody (1% BSA) was... View More
Product Details
MA5-50293
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
14G1A12
Immunogen
Recombinant Human SLN protein (1-31AA)
Conjugate
Form
Liquid
Concentration
1.13 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3091049
Target Information
SLN, also named as Sarcolipin, belongs to the sarcolipin family. It is associated with calcium ATPase SERCA1. It inhibits SERCA pumps. SLN, a key regulator of cardiac sarco (endo)plasmic reticulum (SR) Ca(2+) ATPase, is predominantly expressed in atria and mediates beta-adrenergic responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sarcolipin
Gene Aliases: SLN
UniProt ID: (Human) O00631
Entrez Gene ID: (Human) 6588
calcium ion transport
negative regulation of catalytic activity
negative regulation of protein complex disassembly
regulation of calcium ion transport
sarcoplasmic reticulum calcium ion transport
negative regulation of calcium ion import
negative regulation of calcium ion transmembrane transporter activity
regulation of relaxation of muscle
negative regulation of calcium ion binding
positive regulation of protein depolymerization
regulation of calcium-transporting ATPase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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