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Proteintech
SMAD9 Polyclonal Antibody
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Product Details
16397-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SMAD9 Fusion Protein Ag9490 (1-352 aa encoded by BC011559)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MHSTTPISS LFSFTSPAVK RLLGWKQGDE EEKWAEKAVD SLVKKLKKKK GAMDELERAL SCPGQPSKCV TIPRSLDGRL QVSHRKGLPH VIYCRVWRWP DLQSHHELKP LECCEFPFGS KQKEVCINPY HYRRVETPVL PPVLVPRHSE YNPQLSLLAK FRSASLHSEP LMPHNATYPD SFQQPPCSAL PPSPSHAFSQ SPCTASYPHS PGSPSEPESP YQHSDFRPVC YEEPQHWCSV AYYELNNRVG ETFQASSRSV LIDGFTDPSN NRNRFCLGLL SNVNRNSTIE NTRRHIGKGV HLYYVGGEVY AECVSDSSIF VQSRNCNYQH GFHPATVCKI PSGCSLKVFN NQL (1-352 aa encoded by BC011559)
Target Information
SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, 2, 5, 8 and 9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and 7). SMAD1, 5, 8 and 9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature. Mutations of this gene can lead to pulmonary hypertension, primary 2 (PPH2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HGNC:6774; MAD; MAD homolog 9; Madh6; Mothers against decapentaplegic homolog 9; Mothers against decapentaplegic, drosophila, homolog of, 9; mothers against DPP homolog 9; RP11-421P11.9; SMAD; SMAD 9; SMAD family member 9; SMAD, mothers against DPP homolog 9; Smad8
Gene Aliases: MADH6; Madh8; MADH9; PPH2; SMAD8; SMAD8/9; SMAD8A; SMAD8B; SMAD9
UniProt ID: (Human) O15198, (Rat) O54835, (Mouse) Q9JIW5
Entrez Gene ID: (Human) 4093, (Rat) 85435, (Mouse) 55994
ureteric bud development
response to hypoxia
Mullerian duct regression
transcription, DNA-templated
protein phosphorylation
transforming growth factor beta receptor signaling pathway
BMP signaling pathway
midbrain development
hindbrain development
positive regulation of cell differentiation
positive regulation of transcription, DNA-templated
cartilage development
bone development
cellular response to organic cyclic compound
regulation of transcription, DNA-templated
SMAD protein signal transduction
cellular response to BMP stimulus
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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