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Proteintech
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Immunogen sequence: FHAFGLRYC DAKRMPWGWD YSGSSNLGEL KLLLEEAVML RRLKSDVLSQ LPAKQRKIVV IAPGRINART RAALDAAAKE MTTKDKTKQQ QKDALILFFN RTAEAKIPSV IEYILDLLES GREKFLVFAH HKVVLDAITQ ELERKHVQHI RIDGSTSSAE REDLCQQFQL SERHAVAVLS ITAANMGLTF SSADLVVFAE LFWNPGVLIQ AEDRVHRIGQ TSSVGIHYLV AKGTADDYLW PLIQEKIKVL AEAGLSETNF SEMTESTDYL YKDPKQQKIY DLFQKSFEKE GSDMELLEAA ESFDPGSASG TSGSSSQNMG DTLDESSLTA SPQKKRRFEF FDNWDSFTSP L (605-954 aa encoded by BC016482)
PRKCQ is a calcium-independent, novel isoform that is important in transducing signals in T lymphocytes. Interaction of a T lymphocyte with an antigen-presenting cell results in clustering of the T cell antigen receptor (TCR) and the recruitment of a large signaling complex to the site of cell-cell contact. PRKCQ is essential for TCR-mediated activation. PKC theta plays a role in pathways that link the TCR signaling complex to the activation of NF-kappa B in mature T lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-driven annealing helicase; HepA-related protein; hHARP; mharp; SMARCA-like protein 1; Sucrose nonfermenting protein 2-like 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
Gene Aliases: 6030401P21Rik; AI851716; HARP; HHARP; Mharp; SMARCAL1
UniProt ID: (Human) Q9NZC9, (Rat) B4F769, (Mouse) Q8BJL0
Entrez Gene ID: (Human) 50485, (Rat) 316477, (Mouse) 54380
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